100929-99-5

Basic information

• Product Name: PHE-ARG BETA-NAPHTHYLAMIDE DIHYDROCHLORIDE
• Synonyms: H-PHE-ARG-BETANA 2 HCL;PHE-ARG BETA-NAPHTHYLAMIDE DIHYDROCHLORIDE;phe-arg B-naphthylamide dihydrochloride;phe-argbeta-naphthylamide2HCl;phe-arg β-naphthylamide dihydrochloride;H-Phe-Arg-bNA·2HCl;Phe-Arg beta-naphthylamide;PAβN (dihydrochloride)
• CAS NO: 100929-99-5
• Molecular Formula: C25H32Cl2N6O2
• Molecular Weight: 519.47
• Product Categories: Activity;AlphabeticalEnzyme Substrates;Fluorescent Enzyme Substrates;Fluorescent Probes, Labels, Particles and Stains;Fluorogenic
• Mol File: 100929-99-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• Solubility: Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: PHE-ARG BETA-NAPHTHYLAMIDE DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: PHE-ARG BETA-NAPHTHYLAMIDE DIHYDROCHLORIDE(100929-99-5)
• EPA Substance Registry System: PHE-ARG BETA-NAPHTHYLAMIDE DIHYDROCHLORIDE(100929-99-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 100929-99-5(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Different sources of media describe the Uses of 100929-99-5 differently. You can refer to the following data:
1. Substrate for dipeptidyl aminopeptidase I (cathepsin C).
2. Phe-Arg-beta-naphthylamide Dihydrochloride can be used as a reagent in organic synthesis.
3. Phe-Arg -naphthylamide dihydrochloride has been used to evaluate the contribution of efflux pumps to antimicrobial resistance. It has also been used for minimal inhibitory concentration testing in the presence of an efflux pump inhibitor.

General Description

Phe-Arg β-naphthylamide, a peptidomimetic compound, is an efflux pump inhibitor (EPI). It acts on the major multidrug resistance efflux transporters of Gram-negative bacteria. Phe-Arg -naphthylamide lowers fluoroquinolone resistance in Pseudomonas aeruginosa.