1009359-57-2Relevant academic research and scientific papers
An expedient stereoselective synthesis of the antifungal agent (6 S)-6-[(2 R)-2-hydroxy-6-phenylhexyl]-5,6-dihydro-2H-pyran-2-one
Narsaiah, A. Venkat,Ghogare, Ramesh S.
experimental part, p. 3271 - 3276 (2011/11/30)
An efficient and straightforward stereoselective synthesis of (6S)-6-[(2R)-2-hydroxy-6-phenylhexyl]-5,6-dihydro-2H-pyran-2-one is described. The chiral centers were generated by Sharpless asymmetric epoxidation followed by regioselective epoxide ring open
Stereoselective synthesis of (6S) and (6R)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and their cytotoxic activity against cancer cell lines
Narasimhulu, Manchala,Krishna, Arepalli Sai,Rao, Janapala Venkateswara,Venkateswarlu, Yenamandra
experimental part, p. 2989 - 2994 (2009/06/20)
Stereoselective total synthesis of α,β-unsaturated lactone (1a), isolated from Ravensara crassifolia, has been achieved efficiently starting from chiral 2,3-O-isopropylidene-d-glyceraldehyde (3) followed by asymmetric allylation and ring-closing metathesi
Enantioselective total synthesis of the antifungal agent (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one
Sabitha, Gowravaram,Srinivas, Chitti,Sudhakar, Kadari,Rajkumar, Manne,Maruthi, Chittapragada,Yadav, Jhillu S.
, p. 3886 - 3890 (2008/09/17)
An enantioselective route for the synthesis of (6S)-5,6-dihydro-6-[(2R)-2- hydroxy-6-phenylhexyl]-2H-pyran-2-one is reported. The synthesis is based on epoxide ring opening with a Grignard reagent and stereoselective reduction employing catecholborane as
