1009371-01-0Relevant articles and documents
Design, synthesis and structure-activity relationship of simple bis-amides as potent inhibitors of GlyT1
Jolidon, Synese,Alberati, Daniela,Dowle, Adam,Fischer, Holger,Hainzl, Dominik,Narquizian, Robert,Norcross, Roger,Pinard, Emmanuel
scheme or table, p. 5533 - 5536 (2009/06/18)
Several novel classes of potent and small amide-type inhibitors of glycine transport (GlyT1) were developed through sequential simplification of a benzodiazepinone-lead structure identified from a high-throughput screening. The most potent compounds of these structurally simple classes show low nanomolar inhibition at the GlyT1 target.