100940-57-6

Basic information

• Product Name: GASTRIN I (1-14) (HUMAN)
• Synonyms: gastrin I fragment human 1-14;gastrin i fragment 1-14 human;GASTRIN I HUMAN FRAGMENT 1-14;GASTRIN I (1-14) (HUMAN);PGLU-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP;PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-OH;PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP
• CAS NO: 100940-57-6
• Molecular Formula: C79H100N16O27
• Molecular Weight: 1705.73
• Mol File: 100940-57-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 2164.2±65.0 °C(Predicted)
• Appearance: /
• Density: 1.432±0.06 g/cm3(Predicted)
• Storage Temp.: −20°C
• PKA: 3.38±0.10(Predicted)
• CAS DataBase Reference: GASTRIN I (1-14) (HUMAN)(CAS DataBase Reference)
• NIST Chemistry Reference: GASTRIN I (1-14) (HUMAN)(100940-57-6)
• EPA Substance Registry System: GASTRIN I (1-14) (HUMAN)(100940-57-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 100940-57-6(Hazardous Substances Data)

Usage

General Description

Gastrin I (1-14) is a human peptide hormone that plays a crucial role in the regulation of gastric acid secretion and the maintenance of mucosal integrity in the stomach. It is derived from the precursor protein progastrin and is primarily produced by G cells in the gastric antrum. Gastrin I (1-14) stimulates the release of gastric acid by binding to the cholecystokinin B (CCK-B) receptor on parietal cells in the stomach, leading to increased acid secretion and promotion of gastric motility. Additionally, it also has trophic effects on the gastric mucosa, promoting cell growth and proliferation, and aiding in the repair of damaged tissues. Overall, Gastrin I (1-14) plays a crucial role in maintaining the physiological function of the stomach and is a potential target for therapeutic interventions in gastrointestinal diseases.