1009632-01-2Relevant academic research and scientific papers
Synthesis and biological evaluation of novel bioisosteric analogues of Dimebon
Ivachtchenko, Alexandre Vasilevich,Frolov, Eugene Borisovich,Mitkin, Oleg Dmitrievich,Tkachenko, Sergey Evgenevich,Khvat, Alexandre
scheme or table, p. 446 - 451 (2011/11/06)
In the present paper, we describe the synthesis and biological evaluation for a series of novel 6,9-disubstituted 2-methyl-1,2,3,4,5,6-hexahydroazepino[4,3-b]indoles. These compounds represent unique bioisosteric analogues of Dimebon with promising biological activity against a panel of various targets including some GPCR family members.
