1009796-76-2

Upstream product

• 14204-24-1 N-(phenylthio)succinimide 
• 1009796-72-8 2'-O-[1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl]-6-O-(2,5-dichlorophenyl)-3'-O-levulinoyl-2-N-phenylacetyl-guanosine 
• 1009796-75-1 2'-O-[1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl]-6-O-(2,5-dichlorophenyl)-2-N-phenylacetyl-5'-O-(9-phenyl-xanthen-9-yl)guanosine 3'H-phosphonate triethylammonium salt 

Relevant academic research and scientific papers

Synthesis of 3′,5′-cyclic diguanylic acid (cdiGMP) using 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl as a protecting group for 2′-hydroxy functions of ribonucleosides

We herein report a convenient synthesis of 3′,5′-cyclic diguanylic acid via the modified H-phosphonate approach. The 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl (Cpep) group was used as protecting group for the 2′-hydroxy functions of ribonucleosides. Complete unblocking of the fully protected 3′,5′-cyclic diguanylic acid gave cdiGMP as a homogeneous compound in an excellent yield. Copyright Taylor & Francis Group, LLC.