100981-11-1Relevant articles and documents
Twisting and planarization in push-pull ethylenes
Bernhardt, Paul V.,Koch, Rainer,Moloney, Daniel W.J.,Shtaiwi, Majed,Wentrup, Curt
, p. 515 - 523 (2007/10/03)
As determined by X-ray crystallography, Meldrum's acid derivatives 8-19 feature dihedral angles around the central C=C double bonds between 3 and 83°. Hydrogen bonds between substituents RHN and the carbonyl groups favour near-planarity. Sterically demanding substituents favour large dihedral angles and zwitterionic structures as in formula 20. AM1 calculations of the structures are in excellent agreement with the experimental X-ray data, provided a dielectric field is incorporated (ε = 40). This can be ascribed to the highly polar (zwitterionic) nature of the molecules. It is further predicted that all these molecules, including those that are stabilised in a planar form by intramolecular hydrogen bonds, undergo rapid rotation about the central C=C bonds at room temperature. DFT calculations incorporating a dielectric field model (PCM) are in excellent agreement with the near-perpendicular arrangement of the alkene moiety in 19.
Synthesis of Isopropylidene Malonate Substituted Heterocyclic Ketene N-Acetals
Huang, Zhi-Tang,Shi, Xian
, p. 1321 - 1331 (2007/10/02)
Isopropylidene malonate substituted heterocyclic ketene N,N-acetals 2a-g, N,S-acetals 2h,i and N,O-acetals 2j-l were synthesized from ketene S,S-acetal 1.
