100981-64-4Relevant academic research and scientific papers
SULFONAMIDINES, PROCESS FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
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, (2008/06/13)
Sulfonamidine is disclosed of the general formula (I): EQU1 wherein R is a group selected from 2-(5-methyl-1H-imidazole-4-yl) methyl!thio!ethyl!, 2-5-(dimethylamino)methyl!-2-furanyl!methyl!thio!ethyl, 2-2-(aminoiminomethyl)amino!-4-thiazolyl!methyl!thio!ethyl! or 3-3-(1-piperidinylmethyl)phenoxy! propyl and R 1 is alkyl; or a phenyl group optionally substituted by alkyl, halogen, nitro, alkoxy, alkanoylamino, carboxylic acid, alkoxycarbonyl, dialkylamino, alkylsulphonyl, alkylsulphonylamino or alkylthio; or 1,3,4-thiadiazole-2-yl substituted by alkanoylamino, and the pharmaceutically acceptable salts thereof, as well as a process for preparing these compounds and pharmaceutical compositions containing the same. These compounds have antiulcer activity and can be used in the treatment of peptic ulcers and other pathologies caused or stimulated by gastric acidity.
