100987-04-0

Basic information

• Product Name: 2-AMINO-5-(4-TERT-BUTYLPHENYL)-1,3,4-THIADIAZOLE
• Synonyms: BUTTPARK 24\04-29;5-(4-TERT-BUTYLPHENYL)-1,3,4-THIADIAZOL-2-AMINE;5-(4-TERT-BUTYL-PHENYL)-[1,3,4]THIADIAZOL-2-YLAMINE;2-AMINO-5-(4-TERT-BUTYLPHENYL)-1,3,4-THIADIAZOLE;VITAS-BB TBB000097;TIMTEC-BB SBB004451;1,3,4-thiadiazol-2-amine, 5-[4-(1,1-dimethylethyl)phenyl]-;5-[4-(1,1-dimethylethyl)phenyl]-1,3,4-Thiadiazol-2-amine
• CAS NO: 100987-04-0
• Molecular Formula: C₁₂H₁₅N₃S
• Molecular Weight: 233.33
• Mol File: 100987-04-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 376.9±35.0 °C(Predicted)
• Appearance: /
• Density: 1.168±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.03±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-5-(4-TERT-BUTYLPHENYL)-1,3,4-THIADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-(4-TERT-BUTYLPHENYL)-1,3,4-THIADIAZOLE(100987-04-0)
• EPA Substance Registry System: 2-AMINO-5-(4-TERT-BUTYLPHENYL)-1,3,4-THIADIAZOLE(100987-04-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 100987-04-0(Hazardous Substances Data)

Usage

General Description

2-Amino-5-(4-tert-butylphenyl)-1,3,4-thiadiazole is a synthetic organic compound that belongs to the family of thiadiazoles, which are aromatic compounds containing a five-member heterocycle made up of two nitrogen atoms, two carbon atoms, and one sulfur atom. The compound is particularly noted for its ring structure containing the thiadiazole group, which gives it certain chemical properties. In the compound, the thiadiazole ring is fused to a phenyl group, which carries a tert-butyl substituent. The presence of a single amino group (-NH2) makes the compound potentially reactive and versatile in its interactions with other molecules. The potential uses of such chemicals encompass a wide range, including medicinal chemistry for the potential development of therapeutic drugs. However, the specific properties and uses of 2-Amino-5-(4-tert-butylphenyl)-1,3,4-thiadiazole are subject to further scientific investigation and research.

Upstream product

• 1710-98-1 p-tert-butyl benzoyl chloride 
• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 
• 79-19-6 thiosemicarbazide 
• 100318-99-8 4-tert-butyl-benzaldehyde-thiosemicarbazone 

Downstream Products

• 259794-92-8 5-(4-tert-butyl-phenyl)-[1,2,4]triazole-3,4-diamine 
• 141422-16-4 ethyl 5-<5-(4-tert-butylphenyl)-1,3,4-thiadiazol-2-yl>amino-1H-1,2,3-triazole-4-carboxylate 
• 259794-74-6 [5-(4-tert-Butyl-phenyl)-[1,3,4]thiadiazol-2-yl]-[1-phenyl-meth-(E)-ylidene]-amine 
• 259794-75-7 [5-(4-tert-Butyl-phenyl)-[1,3,4]thiadiazol-2-yl]-[1-(4-chloro-phenyl)-meth-(E)-ylidene]-amine 
• 141422-13-1 2-azido-5-(4-tert-butylphenyl)-1,3,4-thiadiazole 
• 100987-06-2 2-(4-tert-butylphenyl)-7-hydroxy-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one 

Relevant articles and documents

Photoredox catalysis of intramolecular cyclizations with a reusable silica-bound ruthenium complex

Photoredox catalysis with the use of a stable, reusable silica-bound chromophore was applied to the intramolecular cyclization of a series of 2-benzylidenehydrazinecarbothioamides to give 5-phenyl-1,3,4-thiadiazol-2-amines. The catalyst was readily prepar

1,3,4-Thiadiazole-Containing Azo Dyes: Synthesis, Spectroscopic Properties and Molecular Structure

Three series of azo dyes derived from 2-amino-5-aryl-1,3,4-thiadiazoles and aniline, N,N-dimethylaniline and phenol were synthesized in high yields by a conventional diazotization-coupling sequence. The chemical structures of the prepared compounds were confirmed by 1H-NMR, 13C-NMR, IR, UV-Vis spectroscopy, mass spectrometry and elemental analysis. In addition, the X-ray single crystal structure of a representative azo dye was presented. For explicit determination of the influence of a substituent on radiation absorption in UV-Vis range, time-dependent density functional theory calculations were performed.

Studies on the synthesis and bioactivity of some thiadiazole derivatives

Several 2-aryl-3-(4-aryl-1,3,4-thiadiazolyl)-4-thiazolidinones 3 and several other fused heterocycles 5 have been prepared. Most of the compounds 3 have been screened for their fungicidal activity against two fungi Aspergillus clavatus and Aspergillus fum