100992-59-4

Basic information

• Product Name: EPIAMASTATIN HCL
• Synonyms: [(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP HYDROCHLORIDE;(2R,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL;EPIAMASTATIN;EPIAMASTATIN HCL;EPIAMASTATIN HYDROCHLORIDE;H-(2R,3R)-AHMH-VAL-VAL-ASP-OH HCL;(2R,3R)-AHMHA-Val-Val-Asp-OH;(2R,3R)-AHMHA-Val-Val-Asp-OH HCl
• CAS NO: 100992-59-4
• Molecular Formula: C21H39ClN4O8
• Molecular Weight: 511.01
• Product Categories: inhibitor
• Mol File: 100992-59-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 808°Cat760mmHg
• Flash Point: 442.5°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 3.23E-30mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: EPIAMASTATIN HCL(CAS DataBase Reference)
• NIST Chemistry Reference: EPIAMASTATIN HCL(100992-59-4)
• EPA Substance Registry System: EPIAMASTATIN HCL(100992-59-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 100992-59-4(Hazardous Substances Data)

Usage

General Description

Epiamastatin HCl is a synthetic compound that inhibits the activity of matrix metalloproteinases (MMPs), which are enzymes involved in the breakdown of extracellular matrix in various physiological and pathological processes such as tissue remodeling, angiogenesis, and cancer metastasis. By blocking the activity of MMPs, Epiamastatin HCl has potential anti-tumor and anti-metastatic properties, making it a promising candidate for cancer therapy. It is often used in biomedical research to study the role of MMPs in cancer progression and to develop new therapeutic strategies targeting MMPs. Additionally, Epiamastatin HCl may have applications in other disease conditions involving abnormal extracellular matrix remodeling, such as fibrotic diseases.

InChI:InChI=1/C21H38N4O8.ClH/c1-9(2)7-12(22)17(28)20(31)25-16(11(5)6)19(30)24-15(10(3)4)18(29)23-13(21(32)33)8-14(26)27;/h9-13,15-17,28H,7-8,22H2,1-6H3,(H,23,29)(H,24,30)(H,25,31)(H,26,27)(H,32,33);1H