100992-81-2

Basic information

• Product Name: Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2R,3S)- (9CI)
• Synonyms: Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2R,3S)- (9CI)
• CAS NO: 100992-81-2
• Molecular Formula: C₇H₁₂O₃
• Molecular Weight: 144.16838
• Product Categories: CARBOXYLICESTER
• Mol File: 100992-81-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2R,3S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2R,3S)- (9CI)(100992-81-2)
• EPA Substance Registry System: Oxiranecarboxylic acid, 3-propyl-, methyl ester, (2R,3S)- (9CI)(100992-81-2)

Safety Data

• Hazardous Substances Data: 100992-81-2(Hazardous Substances Data)

Upstream product

• 2305-21-7 2-hexen-1-ol 
• 106498-75-3 2,3-epoxyhexanol 
• 96096-69-4 (2R,3S)-2,3-epoxyhexanoic acid 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 92418-71-8 (2R,3R)-2,3-epoxy-1-hexanol 
• 89321-71-1 (2S,3S)-3-propyl-2-oxiranemethanol 
• 96096-69-4 3-propylepoxyethane-2-carboxylic acid 

Relevant articles and documents

A convenient synthesis of aziridine-2-carboxylic esters

Optically active oxirane-2-carboxylic esters, prepared from allylic alcohols employing the Sharpless epoxidation, were treated with sodium azide.The azido alcohols obtained were subsequently converted into aziridine-2-carboxylic esters by reaction with triphenylphosphine, in good yields and with high optical purity.Various racemic oxirane-2-carboxylic esters were subjected to the same sequence of reactions.

A CONVENIENT SYNTHESIS OF OPTICALLY ACTIVE 1H-AZIRIDINE-2-CARBOXYLIC ACIDS (ESTERS).

Optically active glycidic esters, prepared from allylic alcohols employing the Sharpless epoxidation, were treated with sodium azide.In a subsequent reaction with PPh3 the azido alcohols thus obtained were converted into aziridine-2-carboxylic esters of high optical purity in good yields.

Enantioselective Diastereospecific Synthesis of anti-α-Alkyl-β-hydroxy Esters through Cuprate Opening of Glycidic Esters

A diastereospecific chain elongation of the aldehydes 1 to anti-αalkyl-β-hydroxy esters 2 via the intermediates 4 - 7 is described.By means of the Sharpless epoxidation, 2 may be obtained with >90percent ee in either enantiomer.