101-56-4

Basic information

• Product Name: Benzenediazonium, 4-(phenylamino)-, chloride
• Synonyms: P-PHENYLAMINOBENZENEDIAZONIUMCHLORIDE;4-(phenylamino)-benzenediazoniuchloride;4-anilinobenzenediazonium chloride;4-Diazoniodiphenylamine·chloride;Diphenylamine-4-diazonium chloride;4-phenylazanylbenzenediazonium chloride
• CAS NO: 101-56-4
• Molecular Formula: C₁₂H₁₀N₃*Cl
• Molecular Weight: 231.68
• EINECS: 202-954-5
• Mol File: 101-56-4.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: Benzenediazonium, 4-(phenylamino)-, chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenediazonium, 4-(phenylamino)-, chloride(101-56-4)
• EPA Substance Registry System: Benzenediazonium, 4-(phenylamino)-, chloride(101-56-4)

Safety Data

• Hazardous Substances Data: 101-56-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
P-PHENYLAMINOBENZENEDIAZONIUMCHLORIDE is used as a versatile intermediate for the synthesis of various organic compounds. Its diazonium group enables it to participate in diazo coupling reactions, which are crucial for the formation of new organic compounds, including dyes, pigments, and pharmaceuticals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, P-PHENYLAMINOBENZENEDIAZONIUMCHLORIDE is used as a key intermediate in the synthesis of specific pharmaceuticals. Its ability to undergo diazo coupling reactions allows for the creation of novel drug molecules with potential therapeutic applications.
Used in Dye and Pigment Industry:
P-PHENYLAMINOBENZENEDIAZONIUMCHLORIDE is utilized as a starting material for the production of dyes and pigments. Its reactivity and the ability to form a variety of organic compounds make it a valuable component in the development of colorants for various applications, including textiles, plastics, and printing inks.
Used in Research and Development:
In research and development settings, P-PHENYLAMINOBENZENEDIAZONIUMCHLORIDE is employed as a reagent for exploring new chemical reactions and synthesizing novel compounds. Its unique properties and reactivity provide opportunities for scientists to investigate new pathways and mechanisms in organic chemistry.

InChI:InChI=1/C12H10N3.ClH/c13-15-12-8-6-11(7-9-12)14-10-4-2-1-3-5-10;/h1-9,14H;1H/q+1;/p-1

Upstream product

• 101-54-2 N-phenylphenylene-1,4-diamine 

Downstream Products

• 121501-61-9 7-chloro-2-(p-anilinophenyl)-2H-benzotriazolyl-5-amine 

Relevant articles and documents

APPLICATION OF FLUORESCENT TRIAZOLES TO ANALYTICAL CHEMISTRY. IV. DEVELOPMENT OF A NEW FLUORESCENT PROBE FOR BASIC DRUG-α1-ACID GLYCOPROTEIN BINDING MEASUREMENT

A fluorescent probe applicable to protein binding measurement was developed.Several 2-phenylbenzotriazolyl-5-amine derivatives having an amino group on the 2-phenyl ring were synthesized.Their fluorescence characteristics and the binding affinity to α1-acid glycoprotein (α1-AGP) were investigated.They were practically non-fluorescent in aqueous solution, but were highly fluorescent in the presence of α1-AGP.This fluorescence was due to the binding of these compounds to α1-AGP.Of all the compounds synthesized, 7-chloro-2-(p-diethylaminophenyl)-2H-benzotriazolyl-5-amine (CDBA) bound to α1-AGP most strongly and was used as a fluorescent probe.The binding parameters of CDBA were estimated by the fluormetric titration method to be log K = 6.18 and n = 0.40.The fluorescence of CDBA in the α1-AGP solution was markedly quenched in the presence of basic drugs, indicating that these drugs competitively displace CDBA bound to α1-AGP.The binding constants of the basic drugs were calculated, based on the decrease of fluorescence intensity in the presence of the drug.The binding strength of the drugs tested ranged from 4.7 to 6.8 as log K value.Keywords: fluorescent probe; fluorescence characteristics; protein binding; binding parameter; α-acid glycoprotein; competition; basic drug; benzotriazole: 7-chloro-2-(p-diethylaminophenyl)-2H-benzotriazolyl-5-amine