1010104-30-9

Basic information

• Product Name: 1-(4-methyl-1-piperazinyl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-Ethanone
• Synonyms: 1-(4-Methylpiperazin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone;4-(4-Methylpiperazinocarbonyl)methylphenylboronic acid, pinacol ester;1-(4-methyl-1-piperazinyl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-Ethanone
• CAS NO: 1010104-30-9
• Molecular Formula: C₁₉H₂₉BN₂O₃
• Molecular Weight: 344
• Mol File: 1010104-30-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 490.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• PKA: 6.78±0.10(Predicted)
• CAS DataBase Reference: 1-(4-methyl-1-piperazinyl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-Ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methyl-1-piperazinyl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-Ethanone(1010104-30-9)
• EPA Substance Registry System: 1-(4-methyl-1-piperazinyl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-Ethanone(1010104-30-9)

Safety Data

• Hazardous Substances Data: 1010104-30-9(Hazardous Substances Data)

Usage

General Description

1-(4-methyl-1-piperazinyl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-Ethanone is a chemical compound with the molecular formula C19H28BNO2. It is a boronic ester derivative that contains a piperazine ring and a ketone group. 1-(4-methyl-1-piperazinyl)-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-Ethanone is used in various research and pharmaceutical applications, including as a building block for the synthesis of potential drug candidates and other biologically active molecules. It is also utilized as a reagent in organic chemistry reactions, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. As a boronic ester, it has been investigated for its potential in cross-coupling reactions and other synthetic transformations in the field of organic chemistry.

Upstream product

• 349430-56-4 2-(4-bromophenyl)-1-(4-methylpiperazin-1-yl)ethan-1-one 
• 73183-34-3 bis(pinacol)diborane 

Relevant articles and documents

QUINOXALINE DERIVATIVES AS INHIBITORS OF THE TYROSINE KINASE ACTIVITY OF JANUS KINASES

The present invention relates to quinoxaline compound of the formula (I): wherein R1 is carbocyclyl or heterocyclyl, either of which is optionally substituted with 1, 2, 3, 4 or 5 R7; R2 is carbocyclyl or heterocyclyl, either of which is optionally substituted with 1, 2, 3, 4 or 5 R8; R3, R4, R5 and R6 are each independently hydrogen or R9; and R7, R8 and R9 are each independently selected from organic and inorganic substituents, their use in therapy of diseases, in particular diseases mediated by the tyrosine kinase activity of Janus kinases, including JAK-2 and JAK-3 kinases