1010107-93-3Relevant articles and documents
Synthesis and pharmacological validation of a novel series of non-steroidal FXR agonists
Abel, Ulrich,Schlueter, Thomas,Schulz, Andreas,Hambruch, Eva,Steeneck, Christoph,Hornberger, Martin,Hoffmann, Thomas,Perovic-Ottstadt, Sanja,Kinzel, Olaf,Burnet, Michael,Deuschle, Ulrich,Kremoser, Claus
scheme or table, p. 4911 - 4917 (2010/10/03)
To overcome the known liabilities of GW4064 a series of analogs were synthesized where the stilbene double bond is replaced by an oxymethylene or amino-methylene linker connecting a terminal benzoic acid with a substituted heteroaryl in the middle ring po