101040-02-2Relevant academic research and scientific papers
THE KINETIC ANOMERIC EFFECT. ADDITIONS OF NUCLEOPHILES AND OF DIPOLAROPHILES TO N-GLYCOSYLNITRONES AND TO N-PSEUDOGLYCOSYLNITRONES.
Huber, Rolf,Vasella, Andrea
, p. 33 - 58 (2007/10/02)
To prove the hypothesis of the role of a kinetic anomeric effect in the highly diastereoselective additions of nucleophiles and of dipolarophiles to N-glycosylnitrones, we compared these additions to those analogous N-pseudoglycosylnitrones, having a meth
181. Nuchleophilic Additions to N-Glycosylnitrones Asymmetric Synthesis of α-Aminophosphonic Acids
Huber, Rolf,Knierzinger, Andreas,Obrecht, Jean-Pierre,Vasella, Andrea
, p. 1730 - 1747 (2007/10/02)
The hypothesis which explains the diastereoselectivity of the 1,3-dipolar cycloaddition of the N-glycosylnitrones 1-3 leading to the 5,5-disubstituted isoxazolidines 4-6 on the basis of a kinetic anomeric effect predicts that nucleophiles should add to N-
