1010691-58-3Relevant articles and documents
C1-symmetric oxazolinyl sulfoximines as ligands in copper-catalyzed asymmetric mukaiyama aldol reactions
Sedelmeier, Joerg,Hammerer, Tim,Bolm, Carsten
supporting information; experimental part, p. 917 - 920 (2009/04/07)
Aryl-bridged C1-symmetric oxazolinyl sulfoximines are applicable in copper-catalyzed asymmetric Mukaiyama aldol reactions with methyl pyruvate. The resulting a-hydroxy esters have been obtained with up to 94% ee in good yields. They contain a quaternary stereogenic center and represent valuable precursors for biologically active molecules.