1010702-54-1Relevant articles and documents
Two-carbon-elongated HIV-1 protease inhibitors with a tertiary-alcohol- containing transition-state mimic
Wu, Xiongyu,?hrngren, Per,Ekegren, Jenny K.,Unge, Johan,Unge, Torsten,Wallberg, Hans,Samuelsson, Bertil,Hallberg, Anders,Larhed, Mats
, p. 1053 - 1057 (2008/09/20)
A new generation of HIV-1 protease inhibitors encompassing a tertiary-alcohol-based transition-state mimic has been developed. By elongation of the core structure of recently reported inhibitors with two carbon atoms and by varying the P1′ group of the co