101079-48-5

Basic information

• Product Name: 1H-Indole, 3-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-
• CAS NO: 101079-48-5
• Molecular Formula: C16H25NOSi
• Molecular Weight: 275.466
• Mol File: 101079-48-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 3-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 3-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-(101079-48-5)
• EPA Substance Registry System: 1H-Indole, 3-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-(101079-48-5)

Safety Data

• Hazardous Substances Data: 101079-48-5(Hazardous Substances Data)

Upstream product

• 140920-82-7 1-(O-tert-butyldimethylsilyl)-2-<3-(1-phenylsulfonyl)indolyl>ethanol 

Downstream Products

• 140920-82-7 1-(O-tert-butyldimethylsilyl)-2-<3-(1-phenylsulfonyl)indolyl>ethanol 
• 226984-50-5 3-[2-(tert-butyldimethylsilyloxy)ethyl]-1-(p-toluenesulfonyl)indole 
• 226984-53-8 tert-butyl 2-(1-tosyl-1H-indol-3-yl)ethanol 
• 226984-33-4 N-(4-methylphenyl)sulfonyl-3-<(2-methylsulfonyloxo)ethyl>indole 
• 144191-85-5 2-(1H-indol-3-yl)ethyl 2,4-di-O-benzyl-3-deoxy-6-O-(5-aminopentyl)-β-D-glucopyranoside 
• 132132-78-6 2-(1H-Indol-3-yl)ethyl 2,3,4-Tri-O-benzyl-6-O-(5-aminopentyl)-β-D-glucopyranoside 
• 144191-86-6 N-(5-{(2R,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-[2-(1H-indol-3-yl)-ethoxy]-tetrahydro-pyran-2-ylmethoxy}-pentyl)-acetamide 
• 155044-83-0 2-(1phenylsulfonyl-indol-3yl)ethyl-2,3,4-tri-O-benzyl-6-O-trifluoromethylsulfonyl-β-D-glucopyranoside 
• 99655-69-3 3-(2-hydroxyethyl)-1-(benzenesulfonyl)indole 
• 149831-88-9 2-(N-Phenylsulfonylindol-3-yl)-ethyl 4-Deoxy-β-D-glucopyranoside 
• 149857-03-4 2-(N-(phenylsulfonyl)indol-3-yl)ethyl 3-deoxy-β-D-glucopyranoside 
• 149831-75-4 2-(N-Phenylsulfonylindol-3-yl)ethyl β-D-glucopyranoside 
• 149857-02-3 2-(N-(phenylsulfonyl)indol-3-yl)ethyl 2,4,6-tri-O-acetyl-3-deoxy-β-D-glucopyranoside 

Relevant articles and documents

A dipolar cycloaddition approach toward the kopsifoline alkaloid framework

Using a metal-catalyzed domino reaction as the key step, the heterocyclic skeleton of the kopsifoline alkaloid family was constructed by a 1,3-dipolar cycloaddition of a carbonyl ylide dipole derived from a Rh(II)-catalyzed reaction of a diazo ketoester across the indole π-bond. Ring opening of the resulting 1,3-dipolar cycloadduct followed by a reductive dehydroxylation step resulted in the formation of a critical silyl enol ether necessary for the final F-ring closure of the kopsifoline skeleton.