1010795-07-9Relevant academic research and scientific papers
Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay
Krishnamurthy, Malathy,Schirle, Nicole T.,Beal, Peter A.
scheme or table, p. 8914 - 8921 (2009/04/03)
The fluorescent intercalator displacement assay using thiazole orange has been adapted to the study of RNA-binding helix-threading peptides (HTPs). This assay is highly sensitive with HTP-binding RNAs and provides binding affinity data in good agreement w
Macrocyclic helix-threading peptides for targeting RNA
Krishnamurthy, Malathy,Simon, Kristina,Orendt, Anita M.,Beal, Peter A.
, p. 7044 - 7047 (2008/09/18)
Hanging on by a thread: RNA-binding macrocyclic helix-threading peptides were synthesized by solid-phase ring-closing metathesis. The cyclic peptide shows improved affinity to a target RNA over its linear precursor. This compound also binds a naturally oc
