101084-51-9

Basic information

• Product Name: 6-Benzothiazolecarboxamide(6CI)
• Synonyms: 6-Benzothiazolecarboxamide(6CI);Benzothiazole-6-carboxaMide, 96%;Benzo[d]thiazole-6-carboxamide
• CAS NO: 101084-51-9
• Molecular Formula: C₈H₆N₂OS
• Molecular Weight: 178.214
• Product Categories: BENZOTHIAZOLE
• Mol File: 101084-51-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 245-246℃
• Boiling Point: 424.185 °C at 760 mmHg
• Flash Point: 210.34 °C
• Appearance: /
• Density: 1.426 g/cm³
• CAS DataBase Reference: 6-Benzothiazolecarboxamide(6CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Benzothiazolecarboxamide(6CI)(101084-51-9)
• EPA Substance Registry System: 6-Benzothiazolecarboxamide(6CI)(101084-51-9)

Safety Data

• Hazardous Substances Data: 101084-51-9(Hazardous Substances Data)

Usage

Uses

Benzo[d]thiazole-6-carboxamide is a useful reactant for the synthesis of benzothiazolyl pyridyl alkanols which is used to treat elevated levels of aldosterone or abnormal or excessive fibrosis.

Upstream product

• 111962-90-4 2-amino-1,3-benzothiazole-6-carboxamide 
• 23451-96-9 2-amino-5-methylthiophenol 
• 3622-35-3 benzothiazole-6-carboxylic acid 
• 2942-15-6 6-methylbenzothiazole 
• 55439-73-1 1,3-benzothiazole-6-carboxylic acid chloride 

Downstream Products

• 58249-61-9 6-cyano benzothiazole 

Relevant articles and documents

Synthesis and evaluation of 2-pyridylbenzothiazole, 2-pyridylbenzoxazole and 2-pyridylbenzofuran derivatives as 11C-PET imaging agents for β-amyloid plaques

The syntheses and SAR of new series of β-amyloid binding agents are reported. The effort to optimize signal-to-background ratios for these ligands are described. Compounds 8, 21 and 30 displayed desirable lipophilicity and pharmacokinetic properties. Compounds 8 and 21 were evaluated with in vitro autoradiographic studies and in vivo in APP/PS1 transgenic mice. It is shown that it was possible to increase the signal-to-background ratios compared to PIB 1, as demonstrated by compounds 8 and 21.