101084-86-0 Usage
Aromatic amine
2,3,5-Trichlorobenzylamine is classified as an aromatic amine due to its chemical structure, which includes a benzene ring with substituents attached to it.
Common use in synthesis
This compound is frequently used in the synthesis of pharmaceuticals and agrochemicals, indicating its importance in the development of various drugs and chemicals used in agriculture.
Antimicrobial and antifungal properties
2,3,5-Trichlorobenzylamine is known for its ability to inhibit the growth of microorganisms, such as bacteria and fungi, making it a key ingredient in disinfectants and antimicrobial agents.
Wide range of applications
The compound has a broad spectrum of applications in the chemical and pharmaceutical industries, highlighting its versatility and value in different products.
Potential health and environmental hazards
Due to its chemical nature, 2,3,5-Trichlorobenzylamine can pose risks to human health and the environment if not handled properly. It is essential to follow safety precautions and regulations when working with this substance.
Check Digit Verification of cas no
The CAS Registry Mumber 101084-86-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,0,8 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 101084-86:
(8*1)+(7*0)+(6*1)+(5*0)+(4*8)+(3*4)+(2*8)+(1*6)=80
80 % 10 = 0
So 101084-86-0 is a valid CAS Registry Number.
101084-86-0Relevant articles and documents
Systematic Variation of Ligand and Cation Parameters Enables Site-Selective C-C and C-N Cross-Coupling of Multiply Chlorinated Arenes through Substrate-Ligand Electrostatic Interactions
Golding, William A.,Schmitt, Hendrik L.,Phipps, Robert J.
supporting information, p. 21891 - 21898 (2021/01/11)
Use of attractive noncovalent interactions between ligand and substrate is an emerging strategy for controlling positional selectivity. A key question relates to whether fine control on molecules with multiple, closely spaced reactive positions is achievable using typically less directional electrostatic interactions. Herein, we apply a 10-piece "toolkit"comprising of two closely related sulfonated phosphine ligands and five bases, each possessing varying cation size, to the challenge of site-selective cross-coupling of multiply chlorinated arenes. The fine tuning provided by these ligand/base combinations is effective for Suzuki-Miyaura coupling and Buchwald-Hartwig coupling on a range of isomeric dichlorinated and trichlorinated arenes, substrates that would produce intractable mixtures when typical ligands are used. This study develops a practical solution for site-selective cross-coupling to generate complex, highly substituted arenes.
