1011-60-5 Usage
General Description
4-amino-4-phenyl-butanoic acid, also known as Phenibut or β-Phenyl-γ-aminobutyric acid (β-phenyl-GABA), is a chemical compound that belongs to the class of organic compounds known as phenylpropanoic acids. It has central nervous system depressant and anxiolytic effects and is commonly used in Russia for the treatment of anxiety, insomnia, and a variety of other conditions. Its chemical formula is C10H13NO2 and it has a molecular weight of 179.216 g/mol. Despite its medicinal properties, it is not approved for clinical use in the United States and most of Europe, and its excessive consumption can lead to many side effects like dependency and withdrawal symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 1011-60-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,1 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1011-60:
(6*1)+(5*0)+(4*1)+(3*1)+(2*6)+(1*0)=25
25 % 10 = 5
So 1011-60-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO2/c11-9(6-7-10(12)13)8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)
1011-60-5Relevant articles and documents
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Rosenmund,Engels
, p. 209,214 (1951)
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Enzymatic synthesis of chiral γ-amino acids using ω-transaminase
Shon, Minsu,Shanmugavel, Ramachandran,Shin, Giyoung,Mathew, Sam,Lee, Sang-Hyeup,Yun, Hyungdon
supporting information, p. 12680 - 12683 (2015/05/20)
In this study, we successfully synthesized enantiomerically pure (R)- and (S)-γ-amino acids (>99% ee) using ω-transaminase (ω-TA) through kinetic resolution and asymmetric synthesis respectively. The present study demonstrates the high potentiality of ω-TA reaction for the production of chiral γ-amino acids.
Synthesis and some pharmacological properties of alkyl esters of various dl-ω-phenylamino acids
Schulz,Sprung,Kroning
, p. 310 - 313 (2007/10/02)
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