1011-61-6

Basic information

• Product Name: 1-phenylpentane-1,5-diol
• CAS NO: 1011-61-6
• Molecular Formula: C₁₁H₁₆O₂
• Molecular Weight: 180.2435
• Mol File: 1011-61-6.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 339.9°C at 760 mmHg
• Flash Point: 164.8°C
• Density: 1.075g/cm³
• Vapor Pressure: 3.45E-05mmHg at 25°C
• Refractive Index: 1.542
• CAS DataBase Reference: 1-phenylpentane-1,5-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenylpentane-1,5-diol(1011-61-6)
• EPA Substance Registry System: 1-phenylpentane-1,5-diol(1011-61-6)

Safety Data

• Hazardous Substances Data: 1011-61-6(Hazardous Substances Data)

Usage

Usage in skincare and cosmetics

Moisturizing agent and solvent 1-phenylpentane-1,5-diol is commonly used in skincare and cosmetic products for its ability to retain and enhance the skin's moisture levels and effectively dissolve other active ingredients.

Skin barrier improvement

Enhances skin's moisture barrier Pentylene glycol helps improve the skin's natural moisture barrier, which aids in keeping the skin hydrated and healthy.

Penetration enhancer

Facilitates absorption of other active ingredients Due to its ability to mix with other ingredients, 1-phenylpentane-1,5-diol enables better penetration and effectiveness of other active components in skincare and cosmetic products.

Antimicrobial properties

Inhibits bacterial growth This chemical compound has antimicrobial properties that help prevent the growth of bacteria, making it a popular choice for products designed to maintain a clean and healthy skin environment.

Preservation

Extends shelf life of cosmetics 1-phenylpentane-1,5-diol's antimicrobial properties also contribute to the preservation of cosmetic products, extending their shelf life and ensuring their safety for use.

Versatility

Used in a wide range of personal care products Due to its multiple beneficial properties, pentylene glycol is incorporated into various personal care products, including moisturizers, serums, shampoos, and cleansers.

Upstream product

• 109-99-9 tetrahydrofuran 
• 100-52-7 benzaldehyde 
• 10413-17-9 6-phenyltetrahydropyran-2-one 
• 230285-17-3 1-(acetoxy)-1-phenyl-5-(N-phthalimidoxy)pentane 
• 855793-07-6 diethyl 4,8-dimethyl-9-(tetrahydro-pyran-2-yloxy)-nona-3,7-dienyl-1-phosphonate 
• 1501-04-8 Methyl 4-benzoylbutanoate 
• 694-54-2 tetrahydro-2H-2-pyranol 
• 100-58-3 phenylmagnesium bromide 
• 10521-91-2 5-phenylpentan-1-ol 
• 1003-57-2 trans-3-chloro-2-hydroxytetrahydropyran 
• 110-87-2 3,4-dihydro-2H-pyran 
• 1003-57-2 tetrahydro-3-chloro-2H-pyran-2-ol 
• 230285-13-9 5-(tert-butyldiphenylsiloxy)-1-phenyl-1-(2-tetrahydropyranyloxy)pentane 
• 230285-15-1 1-phenyl-5-(N-phthalimidoxy)-1-(2-tetrahydropyranyloxy)pentane 

Downstream Products

• 10413-17-9 6-phenyltetrahydropyran-2-one 
• 75424-63-4 5-oxo-5-phenylpentanal 
• 81418-17-9 (R)-5-hydroxy-5-phenylpentyl acetate 
• 139527-15-4 (S)-5-hydroxy-5-phenylpentyl acetate 
• 3466-80-6 (R)-(+)-6-phenylpiperidine 
• 1616561-87-5 2-ethyl-4-phenyl-1,3-dioxocane 
• 1616561-76-2 5-(allyloxy)-1-phenylpentan-1-ol 
• 112607-33-7 (+)-(R)-δ-(phenyl)-δ-valerolactone 
• 4203-44-5 2-phenyltetrahydropyran 
• 13159-16-5 5-phenyl-4-penten-1-ol 
• 10413-10-2 6-phenyltetrahydro-2H-pyran-2-ol 
• 1011-62-7 5-hydroxy-1-phenylpentan-1-one 
• 1173931-49-1 5-bromo-5-phenylpentan-1-ol 
• 3466-80-6 2-phenylpiperidine 

Relevant articles and documents

Cp*Ir complex-catalyzed N-heterocyclization of primary amines with diols: A new catalytic system for environmentally benign synthesis of cyclic amines

(Chemical Equation Presented) A new efficient method for the N-heterocyclization of primary amines with diols catalyzed by a Cp*Ir complex was developed. A variety of five-, six-, and seven-membered cyclic amines were synthesized in good to excellent yields with the formation of only water as a byproduct. A two-step asymmetric synthesis of (S)-2-phenylpiperidine was also achieved using (R)-1-phenylethylamine as a starting primary amine.

Copper-mediated displacements of allylic THP ethers on a bisphosphonate template

The copper-mediated displacement of allylic THP ethers by Grignard reagents has been examined in a system that contains a geminal bisphosphonate ester. With Grignard reagents derived from several aromatic halides or benzyl bromide the displacement proceed

A phosphine-free iron complex-catalyzed synthesis of cycloalkanes: Via the borrowing hydrogen strategy

Herein we report a diaminocyclopentadienone iron tricarbonyl complex catalyzed synthesis of substituted cyclopentane, cyclohexane and cycloheptane compounds using the borrowing hydrogen strategy in the presence of various substituted primary and secondary 1,n diols as alkylating reagents. Deuterium labeling experiments confirm that the diols were the hydride source in this cascade process. This journal is

Aryl Boronic Acid Catalysed Dehydrative Substitution of Benzylic Alcohols for C?O Bond Formation

A combination of pentafluorophenylboronic acid and oxalic acid catalyses the dehydrative substitution of benzylic alcohols with a second alcohol to form new C?O bonds. This method has been applied to the intermolecular substitution of benzylic alcohols to form symmetrical ethers, intramolecular cyclisations of diols to form aryl-substituted tetrahydrofuran and tetrahydropyran derivatives, and intermolecular crossed-etherification reactions between two different alcohols. Mechanistic control experiments have identified a potential catalytic intermediate formed between the aryl boronic acid and oxalic acid.