1011301-29-3

Basic information

• Product Name: Tenovin 6 (Hydrochloride)
• Synonyms: Tenovin 6 (Hydrochloride);N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide hydrochloride (1:1);Tenovin-6 HCl, >=98%;Tenovin-6.HCl
• CAS NO: 1011301-29-3
• Molecular Formula: C25H35ClN4O2S
• Molecular Weight: 491.089
• Mol File: 1011301-29-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: Tenovin 6 (Hydrochloride)(CAS DataBase Reference)
• NIST Chemistry Reference: Tenovin 6 (Hydrochloride)(1011301-29-3)
• EPA Substance Registry System: Tenovin 6 (Hydrochloride)(1011301-29-3)

Safety Data

• Hazardous Substances Data: 1011301-29-3(Hazardous Substances Data)

Usage

Description

Tenovin 6 (Hydrochloride) is a small molecule activator of p53 transcriptional activity, which plays a crucial role in the regulation of the cell cycle and apoptosis. It is also a potent inhibitor of SIRT1 and SIRT2, enzymes that are involved in various cellular processes, including DNA repair, metabolism, and aging. Tenovin 6 (Hydrochloride) has garnered significant interest due to its potential therapeutic applications in various fields.

Uses

Used in Pharmaceutical Industry:
Tenovin 6 (Hydrochloride) is used as a therapeutic agent for its potential anti-cancer properties. It targets and inhibits SIRT1 and SIRT2, which are known to be overexpressed in various types of cancer cells. By inhibiting these enzymes, Tenovin 6 (Hydrochloride) can promote apoptosis and suppress tumor growth, making it a promising candidate for cancer treatment.
Used in Aging Research:
In the field of aging research, Tenovin 6 (Hydrochloride) is used as a research tool to study the role of SIRT1 and SIRT2 in the aging process. By inhibiting these enzymes, researchers can gain insights into their contribution to cellular aging and the development of age-related diseases.
Used in Neurodegenerative Disease Research:
Tenovin 6 (Hydrochloride) is also used in the study of neurodegenerative diseases, such as Alzheimer's and Parkinson's, where the role of SIRT1 and SIRT2 has been implicated. Inhibiting these enzymes with Tenovin 6 (Hydrochloride) can help researchers understand their involvement in the pathology of these diseases and potentially develop novel therapeutic strategies.
Used in Drug Delivery Systems:
To enhance the bioavailability and therapeutic efficacy of Tenovin 6 (Hydrochloride), various drug delivery systems are being explored. These systems aim to improve the delivery of the compound to target cells and tissues, reducing potential side effects and increasing its overall effectiveness.