1011502-15-0

Basic information

• Product Name: (4-trifluoromethylphenyl)(phenyl)iodonium triflate
• Synonyms: (4-trifluoromethylphenyl)(phenyl)iodonium triflate
• CAS NO: 1011502-15-0
• Molecular Weight: 498.185
• Mol File: 1011502-15-0.mol

Chemical Properties

• CAS DataBase Reference: (4-trifluoromethylphenyl)(phenyl)iodonium triflate(CAS DataBase Reference)
• NIST Chemistry Reference: (4-trifluoromethylphenyl)(phenyl)iodonium triflate(1011502-15-0)
• EPA Substance Registry System: (4-trifluoromethylphenyl)(phenyl)iodonium triflate(1011502-15-0)

Safety Data

• Hazardous Substances Data: 1011502-15-0(Hazardous Substances Data)

Upstream product

• 1493-13-6 trifluorormethanesulfonic acid 
• 455-13-0 4-Iodobenzotrifluoride 
• 71-43-2 benzene 

Downstream Products

• 402-45-9 4-hydroxybenzotrifluoride 
• 1068516-41-5 ethyl 3-oxo-2-(4-(trifluoromethyl)phenyl)butanoate 
• 1454697-59-6 11-phenyl-2-(trifluoromethyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline 
• 1454697-35-8 9-phenyl-7-(trifluoromethyl)-1,2,3,4-tetrahydroacridine 
• 1454697-22-3 9-phenyl-7-(trifluoromethyl)-2,3-dihydro-1H-cyclopenta[b]quinoline 

Relevant articles and documents

Synthesis of phenols and aryl silyl ethers via arylation of complementary hydroxide surrogates

Two transition-metal-free methods to access substituted phenols via the arylation of silanols or hydrogen peroxide with diaryliodonium salts are presented. The complementary reactivity of the two nucleophiles allows synthesis of a broad range of phenols without competing aryne formation, as illustrated by the synthesis of the anesthetic Propofol. Furthermore, silyl-protected phenols can easily be obtained, which are suitable for further transformations.

Efficient and general one-pot synthesis of diaryliodonium triflates: Optimization, scope and limitations

Symmetrical and unsymmetrical diaryliodonium triflates have been synthesized from both electron-deficient and electron-rich arenes and aryl iodides with mCPBA and triflic acid. A thorough investigation of the optimization, scope and limitations has resulted in an improved one-pot protocol that is fast, high-yielding, and operationally simple. The reaction has been extended to the direct synthesis of symmetrical iodonium salts from iodine and arenes, conveniently circumventing the need for aryl iodides.