101161-48-2Relevant academic research and scientific papers
REACTIONS OF 6-(N-METHYLANILINO)-5-(N-PHENYLIMINO)PYRIMIDINE-2,4(3H,5H)-DIONE WITH BENZYL HYDROSULFIDE AND BENZYLAMINE
Sako, Magoichi,Kojima, Yutaka,Hirota, Kosaku,Maki, Yoshifumi
, p. 2525 - 2528 (2007/10/02)
Treatment of 6-(N-methylanilino)-5-(N-phenylimino)pyrimidine-2,4(3H,5H)-dione (2a) with benzyl hydrosulfide or benzylamine under mild conditions without any catalyst resulted in the concurrent occurence of a redox reaction and nucleophilic substitution at the C(6)-position of 2a to give 5-anilino-6-(N-methylanilino)uracil (1a), 6-substituted 5-(N-phenylimino)pyrimidine-2,4(3H,5H)-diones (2b, c), and the oxidation product (dibenzyl disulfide or N-benzylidenebenzylamine).The substitution products 2b, c also oxidized benzyl hydrosulfide and benzylamine under the same conditions.Keywords:-6-substitued 5-(N-phenylimino)pyrimidine-2,4(3H,5H)-dione; benzyl hydrosulfide; benzylamine; redox reaction; 6-substituted 5-anilinouracil
