101169-52-2Relevant academic research and scientific papers
β-fluoroamphetamines via the stereoselective synthesis of benzylic fluorides
Cresswell, Alexander J.,Davies, Stephen G.,Lee, James A.,Roberts, Paul M.,Russell, Angela J.,Thomson, James E.,Tyte, Melloney J.
supporting information; experimental part, p. 2936 - 2939 (2010/09/10)
A range of substituted aryl epoxides undergo efficient ring-opening hydrofluorination upon treatment with 0.33 equiv of BF3-OEt 2 in CH2Cl2 at -20 -°C to give the corresponding syn-fluorohydrins, consistent with a mechanism involving a stereoselective SN1-type epoxide ring-opening process. The benzylic fluoride products of these reactions are valuable templates for further elaboration, as demonstrated by the preparation of a range of aryl-substituted β-fluoroamphetamines.
A unique site-selective reaction of ketones with new recyclable hypervalent iodine(III) reagents based on a tetraphenylmethane structure
Dohi, Toshifumi,Maruyama, Akinobu,Yoshimura, Misaki,Morimoto, Koji,Tohma, Hirofumi,Shiro, Motoo,Kita, Yasuyuki
, p. 2205 - 2207 (2007/10/03)
We have synthesized new recyclable reagents having a tetraphenylmethane backbone and used them in the site-selective α-tosyloxylation of ketones. The Royal Society of Chemistry 2005.
