10118-81-7

Basic information

• Product Name: 4,8-DIHYDROXYQUINOLINE
• Synonyms: 2-(3,4-Dihydroxyphenyl)-2-oxoacetic acid;3,4-Dihydroxy-α-oxobenzeneacetic acid;α-Oxo-3,4-dihydroxybenzeneacetic acid
• CAS NO: 10118-81-7
• Molecular Formula: C₈H₆O₅
• Molecular Weight: 161.16
• Mol File: 10118-81-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 159 °C
• Boiling Point: 445.4°C at 760 mmHg
• Flash Point: 237.3°C
• Appearance: /
• Density: 1.619g/cm³
• Vapor Pressure: 1.02E-08mmHg at 25°C
• Refractive Index: 1.661
• PKA: 2.10±0.54(Predicted)
• CAS DataBase Reference: 4,8-DIHYDROXYQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,8-DIHYDROXYQUINOLINE(10118-81-7)
• EPA Substance Registry System: 4,8-DIHYDROXYQUINOLINE(10118-81-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 10118-81-7(Hazardous Substances Data)

Usage

General Description

4,8-Dihydroxyquinoline is a chemical compound with the molecular formula C9H7NO2. It is a derivative of quinoline and is known for its antioxidant and chelating properties. It has been studied for its potential use in the treatment of neurological disorders and has shown promise in reducing oxidative stress and protecting against neurodegenerative diseases. 4,8-Dihydroxyquinoline has also been used in the development of new materials for applications in areas such as catalysis, optoelectronics, and sensors. Its unique chemical structure and properties make it a versatile compound with potential applications in various fields of science and technology.

InChI:InChI=1/C8H6O5/c9-5-2-1-4(3-6(5)10)7(11)8(12)13/h1-3,9-10H,(H,12,13)

Upstream product

• 117-39-5 quercetol 
• 89662-01-1 O,O-diethoxycarbonylprotocatechuic acid 
• 99-50-3 3,4-Dihydroxybenzoic acid 
• 7732-18-5 water 
• 861377-46-0 (3,4-bis-ethoxycarbonyloxy-phenyl)-glyoxylonitrile 
• 86787-79-3 3,4-bis-ethoxycarbonyloxy-benzoyl chloride 
• 151-50-8 potassium cyanide 

Relevant articles and documents

The influence of the host-guest interaction on the oxidation of natural flavonoid dyes

The influence of the molecular cavity protection on degradation processes of bioorganic compounds quercetin and luteolin used as the original dyes in old tapestries was studied. The degradation processes were studied by electrochemical methods in aqueous media. The products of the exhaustive electrolysis were separated and identified by GC-MS analysis. Cyclic voltammetry characteristics indicate that the inclusion complex is formed. The inclusion affects the redox potentials of both oxidation waves related to the different dissociation forms of the flavonoid molecule. It was shown that decomposition products formed by the oxidation of quercetin are stabilized in the cavity of β-cyclodextrin, including the main oxidation product 2(3',4'- dihydroxybenzoyl)-2,4,6-trihydroxybenzofuran-3(2H)-one. The formation of the 1:1 inclusion complex of luteolin with β-cyclodextrin is supported by the enhancement of fluorescence intensity. In the case of quercetin, a decrease of fluorescence intensity occurs when 1:1 inclusion complex with β-cyclodextrin is formed.