1012051-90-9

Basic information

• Product Name: N,N''-[(1R,2R)-1,2-diphenyl-1,2-ethanediyl]bis[N'-[3,5-bis(trifluoroMethyl)phenyl]-Thiourea
• Synonyms: N,N''-[(1R,2R)-1,2-diphenyl-1,2-ethanediyl]bis[N'-[3,5-bis(trifluoroMethyl)phenyl]-Thiourea;N,N'-[(1R,2R)-1,2-Diphenyl-1,2-ethanediyl]bis[N'-[3,5- bis(trifluoromethyl)phenyl]thiourea],99%e.e.;N,N'-[(1R,2R)-1,2-Diphenyl-1,2-ethanediyl]bis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea], 98%, (99% ee)
• CAS NO: 1012051-90-9
• Molecular Formula: C₃₂H₂₂F₁₂N₄S₂
• Molecular Weight: 754.6547184
• Mol File: 1012051-90-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 194-196 °C
• Boiling Point: 612.2±65.0 °C(Predicted)
• Appearance: /
• Density: 1.489±0.06 g/cm3(Predicted)
• PKA: 11.18±0.70(Predicted)
• CAS DataBase Reference: N,N''-[(1R,2R)-1,2-diphenyl-1,2-ethanediyl]bis[N'-[3,5-bis(trifluoroMethyl)phenyl]-Thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N,N''-[(1R,2R)-1,2-diphenyl-1,2-ethanediyl]bis[N'-[3,5-bis(trifluoroMethyl)phenyl]-Thiourea(1012051-90-9)
• EPA Substance Registry System: N,N''-[(1R,2R)-1,2-diphenyl-1,2-ethanediyl]bis[N'-[3,5-bis(trifluoroMethyl)phenyl]-Thiourea(1012051-90-9)

Safety Data

• Hazardous Substances Data: 1012051-90-9(Hazardous Substances Data)

Usage

General Description

N,N''-[(1R,2R)-1,2-diphenyl-1,2-ethanediyl]bis[N'-[3,5-bis(trifluoroMethyl)phenyl]-Thiourea, also known as DPTU, is a chemical compound used as a curing agent in the production of polyurethane. It is a bis(thiourea) compound with a 1,2-diphenylethane backbone and trifluoromethylphenyl substituents. The compound is known for its high thermal stability and its ability to promote fast curing of polyurethane coatings and adhesives, making it suitable for use in various industrial applications. DPTU is also used as a crosslinking agent in the production of rubber and elastomers, and it is known for its effectiveness in promoting good adhesion and high tensile strength in the final products. However, it is important to handle DPTU with caution as it is considered toxic and may cause skin and eye irritation upon contact.

Upstream product

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Relevant articles and documents

Bianthryl-based organocatalysts for the asymmetric Henry reaction of fluoroketones

We have developed a catalytic system based on bianthrylbis(thiourea) for the asymmetric Henry reaction of fluoroketones and nitroalkanes that resulted from the screening of a library containing 31 chiral non-racemic organocatalysts. The corresponding adducts were isolated in up to 6 times shorter reaction time in comparison with the previously published organocatalysts. High levels of stereocontrol have been generally observed, with measured product enantiomeric excesses up to 97% and diastereomeric ratio 3:2 (anti/syn). The above-mentioned catalysts have been successfully applied to the total asymmetric synthesis of CF3-tethered (S)-halostachines, which has proved that this method constitutes an easy entry to similar enantiopure compounds.

Organocatalytic enantioselective Mannich-type reaction of phosphorus ylides: Synthesis of chiral N-Boc-β-amino-α-methylene carboxylic esters

The first asymmetric Mannich-type reaction of stabilized phosphorus ylides and N-Boc aldimines was described promoted by a readily available and recyclable chiral bisthiourea organocatalyst. Subsequent reaction with formalin smoothly provides N-Boc-β-amino-α-methylene carboxylic esters in a highly enantiomerically enriched form (up to 96% ee). Copyright