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1012057-47-4

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1012057-47-4 Usage

General Description

4-Hydroxy-7-methoxy-6-nitroquinazoline is a chemical compound with the molecular formula C9H7N3O4. It is a quinazoline derivative with a hydroxyl group, a methoxy group, and a nitro group attached to the quinazoline ring. 4-Hydroxy-7-methoxy-6-nitroquinazoline has potential biological activities and has been studied for its potential use in pharmaceuticals. It is also used in research and development as a building block for the synthesis of other organic compounds. The chemical structure and properties of 4-Hydroxy-7-methoxy-6-nitroquinazoline make it an interesting target for further investigation in the fields of medicinal chemistry and drug development.

Check Digit Verification of cas no

The CAS Registry Mumber 1012057-47-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,2,0,5 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1012057-47:
(9*1)+(8*0)+(7*1)+(6*2)+(5*0)+(4*5)+(3*7)+(2*4)+(1*7)=84
84 % 10 = 4
So 1012057-47-4 is a valid CAS Registry Number.
InChI:InChI=1S/C9H7N3O4/c1-16-8-3-6-5(2-7(8)12(14)15)9(13)11-4-10-6/h2-4H,1H3,(H,10,11,13)

1012057-47-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-methoxy-6-nitro-1H-quinazolin-4-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1012057-47-4 SDS

1012057-47-4Relevant articles and documents

Phenyl [...] compound and its preparation method, pharmaceutical composition, drug use (by machine translation)

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Paragraph 0272; 0273; 0278; 0279, (2016/10/27)

The invention provides a phenylurea coupling quinazoline compound or a pharmaceutically acceptable salt thereof represented by formula (I), wherein R1 represents H, represents Br, Cl or F, represents -CH3, -CH2-CH3, -CH2(CH3)2 or -CF3, represents -O-CH3, -O-CH2-CH3 or -O-CH2(CH3)2, or represents -C[triple bond]CH or -C[triple bond]N; n1 is 1, 2, 3, 4 or 5; one of R2 and R3 is a group represented by formula (II); R4 represents H, represents Br, Cl or F, represents -CH3, -CH2-CH3, -CH2(CH3)2 or -CF3, represents -O-CH3, -O-CH2-CH3 or -O-CH2(CH3)2, represents -NH2, or represents -NO2; n2 is 1, 2, 3, 4 or 5; and the other one of R2 and R3 represents H, -O-CH3, -O-CH2-CH3, -O-CH2(CH3)2, or the following groups.

TARTRATE SALTS OF QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY

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Page/Page column 74, (2009/04/24)

The present invention relates to tartrate salts of quinazoline containing zinc-binding moiety based derivatives that are inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer. The tartrate salts may further act as HDAC inhibitors.

MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS

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Page/Page column 129-130, (2008/06/13)

The present invention relates to the compositions, methods, and applications of a novel approach to selective inhibition of several cellular or molecular targets with a single small molecule. More specifically, the present invention relates to multi-functional small molecules wherein one functionality is capable of inhibiting histone deacetylases (HDAC) and the other functionality is capable of inhibiting a different cellular or molecular pathway involved in aberrant cell proliferation, differentiation or survival.

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