101222-19-9

Basic information

• Product Name: L-Valyl-L-valine benzyl ester
• Synonyms: L-Valyl-L-valine benzyl ester
• CAS NO: 101222-19-9
• Molecular Weight: 306.405
• Mol File: 101222-19-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: L-Valyl-L-valine benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valyl-L-valine benzyl ester(101222-19-9)
• EPA Substance Registry System: L-Valyl-L-valine benzyl ester(101222-19-9)

Safety Data

• Hazardous Substances Data: 101222-19-9(Hazardous Substances Data)

Upstream product

• 13734-41-3 t-Boc-L-valine 
• 21760-98-5 L-valine benzyl ester 
• 122751-34-2 Boc-Val-OPyCl 
• 16652-76-9 L-valine benzyl ester p-toluenesulfonate salt 
• 77443-49-3 (S)-benzyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)-3-methylbutanoate 
• 66866-46-4 C₁₅H₂₇NO₆ 
• 24601-74-9 (S)-4-isopropyloxazolidine-2,5-dione 

Downstream Products

• 149836-38-4 Z-Gly-Pro-Arg(NO₂)-Val-Val-OBzl 
• 122299-14-3 H-Thr-Asn-Val-Val-OH 
• 133898-42-7 Z-Thr-Asn-Val-Val-OBzl 
• 1222260-35-6 C₂₀H₃₃N₅O₃ 
• 1242760-40-2 Boc-Ala-Val-Val-OCH₂Ph 
• 99429-52-4 Val-Val-Val-OBzl 
• 3918-94-3 Val-Val 
• 149836-40-8 Z(OMe)-Arg(NO₂)-Val-Val-OBzl 
• 133898-41-6 Boc-Asn-Val-Val-OBzl 
• 99429-50-2 Boc-Val-Val-Val-OBzl 

Relevant articles and documents

Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP

We recently reported the systematic ligand-based rational design and synthesis of monovalent Smac mimetics that bind preferentially to the BIR2 domain of the anti-apoptotic protein XIAP. Expanded structure-activity relationship (SAR) studies around these peptidomimetics led to compounds with significantly improved selectivity (>60-fold) for the BIR2 domain versus the BIR3 domain of XIAP. The potent and highly selective IAP antagonist 8q (ML183) sensitized TRAIL-resistant prostate cancer cells to apoptotic cell death, highlighting the merit of this probe compound as a valuable tool to investigate the biology of XIAP.

Amino acids and peptides. XVII. Synthesis of peptides related to N-terminal portion of fibrin alpha-chain and their inhibitory effect on fibrinogen/thrombin clotting.

Various peptides related to N-terminal portion of fibrin alpha-chain were synthesized by the solution method and the solid-phase method, and their inhibitory effect on fibrinogen/thrombin clotting was examined. Extension of peptide chain from N-terminal t

Synthesis and structure-activity relationships of amastatin analogues, inhibitors of aminopeptidase A

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