101222-80-4Relevant articles and documents
Sequence specificity of DNA alkylation by the unnatural enantiomer of CC-1065 and its synthetic analogues
Hurley,Warpehoski,Lee,McGovren,Scahill,Kelly,Mitchell,Wicnienski,Gebhard,Johnson,Bradford
, p. 4633 - 4649 (2007/10/02)
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Total Synthesis of U-71,184, A Potent New Antitumor Agent Modeled on CC-1065
Warpehoski, M.A.
, p. 4103 - 4106 (2007/10/02)
The synthesis of U-71,184 (2), a highly potent analog of the novel antitumor antibiotic CC-1065, is described, the penultimate step of which involves the unmasking of a p-hydroxy phenethyl mesylate, which undergoes facile intramolecular elimination to aff