10124-78-4

Basic information

• Product Name: 2-NAPHTHYL ISOCYANIDE 97
• Synonyms: 2-NAPHTHYL ISOCYANIDE 97;2-Naphtyl isocyanide;2-isocyanonaphthalene;2-Naphthyl isocyanide 95%
• CAS NO: 10124-78-4
• Molecular Formula: C₁₁H₇N
• Molecular Weight: 153.183
• Product Categories: Isocyanides;Nitrogen Compounds;Organic Building Blocks
• Mol File: 10124-78-4.mol
• Article Data: 12

Chemical Properties

• Melting Point: 60-64 °C(lit.)
• Appearance: /
• Storage Temp.: ?20°C
• CAS DataBase Reference: 2-NAPHTHYL ISOCYANIDE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NAPHTHYL ISOCYANIDE 97(10124-78-4)
• EPA Substance Registry System: 2-NAPHTHYL ISOCYANIDE 97(10124-78-4)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 10124-78-4(Hazardous Substances Data)

Usage

General Description

2-Naphthyl isocyanide 97 is a chemical compound with the formula C12H9N. It is a highly flammable, colorless to yellow liquid that is commonly used as a building block in organic synthesis and pharmaceutical production. 2-Naphthyl isocyanide 97 is known for its strong odor and should be handled with proper protective equipment and in a well-ventilated area to avoid inhalation of its fumes. It is also a known irritant to the skin, eyes, and respiratory system, so precautions should be taken when working with this substance. Additionally, 2-Naphthyl isocyanide 97 is sensitive to air and light and should be stored in a cool, dark place to prevent degradation.

InChI:InChI=1/C11H7N/c1-12-11-7-6-9-4-2-3-5-10(9)8-11/h2-8H

Upstream product

• 91-59-8 naphthalen-2-ylamine 
• 91-63-4 2-methylquinoline 
• 67-66-3 chloroform 
• 4423-74-9 2-formamidonaphthalene 

Downstream Products

• 1280185-88-7 2-(2-acetylphenylamino)-2-(4-methoxyphenyl)-N-(naphthalen-2-yl)acetamide 
• 1280185-87-6 2-(2-acetylphenylamino)-N-(naphthalen-2-yl)-2-(4-nitrophenyl)acetamide 
• 18271-22-2 N-(naphthalen-2-yl)benzamide 

Relevant articles and documents

Correlation between HOMO alignment and contact resistance in molecular junctions: Aromatic thiols versus aromatic isocyanides

Understanding electron transport in metal-molecule-metal (MMM) junctions is of great importance for the advancement of molecular electronics. Critical factors that determine conductivity in a MMM junction include the nature of metal-molecule contacts and

Enantioselective Synthesis of Azetidines through [3 + 1]-Cycloaddition of Donor-Acceptor Aziridines with Isocyanides

The enantioselective [3 + 1]-cycloaddition of racemic donor-acceptor (D-A) aziridines with isocyanides was first realized under mild reaction conditions using a chiral N,N′-dioxide/MgIIcomplex as catalyst, providing a facile route to enantioenriched exo-imido azetidines with good to excellent yield (up to 99%) and enantioselectivity (up to 94% ee). An obvious chiral amplification effect was observed in this system, and an explanation was elucidated based on the experimental investigation and X-ray crystal structure of the enantiomerically pure catalyst.

Organophosphine-free copper-catalyzed isothiocyanation of amines with sodium bromodifluoroacetate and sulfur

A copper-catalyzed isothiocyanation of amines with sodium bromodifluoroacetate and sulfur in the absence of organophosphine has been established. This approach represents a simple and efficient one-pot synthesis of isothiocyanates, and features excellent functional group tolerance and the use of a cheap, safe and odorless sulfur source. Moreover, this process could directly provide isothiocyanate analogous bioactive molecules, thiocarbonyl-containing pesticides and facile construction of benzoxazole and benzimidazole frames.