101251-12-1

Basic information

• Product Name: 4-AMino-2-broMophenetole
• Synonyms: 4-AMino-2-broMophenetole;3-bromo-4-ethoxyBenzenamine;3-BROMO-4-ETHOXYANILINE
• CAS NO: 101251-12-1
• Molecular Formula: C₈H₁₀BrNO
• Molecular Weight: 216.0751
• Mol File: 101251-12-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-AMino-2-broMophenetole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMino-2-broMophenetole(101251-12-1)
• EPA Substance Registry System: 4-AMino-2-broMophenetole(101251-12-1)

Safety Data

• Hazardous Substances Data: 101251-12-1(Hazardous Substances Data)

Upstream product

• 7647-01-0 hydrogenchloride 
• 100-29-8 1-ethoxy-4-nitrobenzene 
• 583-19-7 beta-bromophenetole 
• 62-44-2 4-ethoxyacetanilide 
• 860767-63-1 bis-(4-ethoxy-3-bromo-phenyl)-diazene-N-oxide 
• 119532-30-8 acetic acid-(4-ethoxy-3-bromo-anilide) 
• 58244-42-1 2-bromo-1-ethoxy-4-nitrobenzene 

Downstream Products

• 25021-67-4 1,3-Bis-(3-bromo-4-ethoxy-phenyl)-2-thiourea 
• 109506-95-8 N,N-dimethyl-alanine-(4-ethoxy-3-bromo-anilide) 
• 152335-97-2 6,8-Dibromo-2-(3-Bromo-4-ethoxyphenyl)-imidazo[1,5,a]quinoxaline-1,3(2H,5H)-dione 
• 1237390-14-5 1-(2-Nitrophenyl)-3-(3-bromo-4-ethoxyphenyl)-imidazoline-2,4(1H,3H)-dione 
• 1237390-13-4 N'-(2-chloroacetyl)-N-(2-nitrophenyl)-N'-(3-bromo-4-ethoxyphenyl)-urea 
• 142880-07-7 2-(3-Bromo-4-ethoxyphenyl)-imidazo[1,5-a]quinoxaline-1,3(2H,5H)-dione 
• 152335-95-0 N-(2-Nitrophenyl)-N'-(3-bromo-4-ethoxyphenyl)-urea 
• 846023-36-7 3-bromo-4-ethoxyanilino-N-(2,4-dichloro-5-methoxyphenyl)-2-cyano-2-propenamide 
• 25021-69-6 2-bromo-1-ethoxy-4-isothiocyanato-benzene 
• 25020-70-6 1-(3-bromo-4-ethoxy-phenyl)-3-[4-(2,4-dimethyl-thiazol-5-yl)-phenyl]-thiourea 
• 25020-43-3 1-(3-bromo-4-ethoxy-phenyl)-3-[4-(4,5-dimethyl-thiazol-2-yl)-phenyl]-thiourea 
• 25020-68-2 1-(3-bromo-4-ethoxy-phenyl)-3-[4-(4-methyl-thiazol-5-yl)-phenyl]-thiourea 
• 25020-40-0 1-(3-bromo-4-ethoxy-phenyl)-3-[4-(4-methyl-thiazol-2-yl)-phenyl]-thiourea 
• 25020-37-5 1-(3-bromo-4-ethoxy-phenyl)-3-(4-thiazol-2-yl-phenyl)-thiourea 

Relevant articles and documents

BETA-SUBSTITUTED BETA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS AND USES THEREOF

β-Substituted β-amino acids, β-substituted β-amino acid derivatives, and β-substituted β-amino acid analogs and (bio)isosteres and their use as chemotherapeutic agents are disclosed. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and (bio)isosteres are selective LAT1/4F2hc substrates and exhibit rapid uptake and retention in tumors expressing the LAT1/4F2hc transporter. Methods of synthesizing the β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and methods of using the compounds for treating cancer are also disclosed. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs exhibit selective uptake in tumor cells expressing the LAT1/4F2hc transporter and accumulate in cancerous cells when administered to a subject in vivo. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and (bio)isosteres exhibit cytotoxicity toward several tumor types.