10126-37-1 Usage
General Description
2-BROMO-5-METHOXY-N,N-DIMETHYLBENZYLAMINE is a chemical compound that is used in organic synthesis and research. It is a substituted benzylamine with a bromine atom and a methoxy group attached to the benzene ring. The N,N-dimethyl functional group is also present, which makes it a tertiary amine. 2-BROMO-5-METHOXY-N,N-DIMETHYLBENZYLAMINE is commonly used as a reagent in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Its unique structure and properties make it a valuable building block for the preparation of diverse chemical products. Additionally, it is important to handle this compound with care, as it may be harmful if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 10126-37-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,2 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10126-37:
(7*1)+(6*0)+(5*1)+(4*2)+(3*6)+(2*3)+(1*7)=51
51 % 10 = 1
So 10126-37-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H14BrNO/c1-12(2)7-8-6-9(13-3)4-5-10(8)11/h4-6H,7H2,1-3H3
10126-37-1Relevant articles and documents
Cationic chalcone antibiotics. Design, synthesis, and mechanism of action
Nielsen, Simon F.,Larsen, Mogens,Boesen, Thomas,Sch?nning, Kristian,Kromann, Hasse
, p. 2667 - 2677 (2007/10/03)
This paper describes how the introduction of "cationic" aliphatic amino groups in the chalcone scaffold results in potent antibacterial compounds. It is shown that the most favorable position for the aliphatic amino group is the 2-position of the B-ring, in particular in combination with a lipophilic substituent in the 5-position of the B-ring. We demonstrate that the compounds act by unselective disruption of cell membranes. Introduction of an additional aliphatic amino group in the á-ring results in compounds that are selective for bacterial membranes combined with a high antibacterial activity against both Gram-positive and -negative pathogens. The most potent compound in this study (78) has an MIC value of 2 μM against methicillin resistant Staphylococus aureus.
