101273-81-8 Usage
General Description
2-O-TOLYL-4H-ISOQUINOLINE-1,3-DIONE is a chemical compound with the molecular formula C16H11NO2. It is a derivative of isoquinoline and is primarily used in the production of pharmaceuticals and organic synthesis. 2-O-TOLYL-4H-ISOQUINOLINE-1,3-DIONE is known for its biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It has been studied for its potential use in treating various diseases and conditions, such as cancer, neurodegenerative disorders, and inflammatory diseases. 2-O-TOLYL-4H-ISOQUINOLINE-1,3-DIONE is an important intermediate in the synthesis of various biologically active compounds and has potential applications in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 101273-81-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,2,7 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 101273-81:
(8*1)+(7*0)+(6*1)+(5*2)+(4*7)+(3*3)+(2*8)+(1*1)=78
78 % 10 = 8
So 101273-81-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO2/c1-11-6-2-5-9-14(11)17-15(18)10-12-7-3-4-8-13(12)16(17)19/h2-9H,10H2,1H3
101273-81-8Relevant articles and documents
Superelectrophiles in Synthesis: Preparation of Aromatic Imides
Kennedy, Sean H.,Schaeff, Mark N.,Klumpp, Douglas A.
, p. 14133 - 14140 (2019/10/16)
Aromatic carboxylic acids are found to undergo reactions with isocyanates, wherein triflic acid promotes the formation of aromatic imide products in fair to good yields. It is proposed that the carboxylic acid group directs the isocyanate electrophile to
Specific inhibitor of puromycin-sensitive aminopeptidase with a homophthalimide skeleton: Identification of the target molecule and a structure-activity relationship study
Komoda, Masato,Kakuta, Hiroki,Takahashi, Hiroyasu,Fujimoto, Yasuyuki,Kadoya, Shizuo,Kato, Fuminori,Hashimoto, Yuichi
, p. 121 - 131 (2007/10/03)
2-(2,6-Diethylphenyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione (2: PIQ-22) was found to be a potent and specific inhibitor of puromycin-sensitive aminopeptidase (PSA). Lineweaver-Burk plot analysis showed that PSA is inhibited by PIQ-22 in a non-competitive manner. Structure-activity relationship studies indicated that tautomerism of the imidobenzoylketone group in the cyclic imide moiety of the PIQ-22 skeleton is important for the inhibitory activity.
