1012860-07-9

Basic information

• Product Name: (4-chloro-2-trifluoromethyl-phenyl)carbamic acid 1-[(3-methanesulfonyl-allylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester
• Synonyms: (4-chloro-2-trifluoromethyl-phenyl)carbamic acid 1-[(3-methanesulfonyl-allylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester
• CAS NO: 1012860-07-9
• Molecular Weight: 663.074
• Mol File: 1012860-07-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-chloro-2-trifluoromethyl-phenyl)carbamic acid 1-[(3-methanesulfonyl-allylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chloro-2-trifluoromethyl-phenyl)carbamic acid 1-[(3-methanesulfonyl-allylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester(1012860-07-9)
• EPA Substance Registry System: (4-chloro-2-trifluoromethyl-phenyl)carbamic acid 1-[(3-methanesulfonyl-allylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester(1012860-07-9)

Safety Data

• Hazardous Substances Data: 1012860-07-9(Hazardous Substances Data)

Upstream product

• 1012860-24-0 {(3R)-1-[2-(allylamino)-2-oxoethyl]2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl}methyl[4-chloro-2-(trifluoromethyl)phenyl]carbamate 
• 3680-02-2 methyl ethenyl sulphone 

Relevant articles and documents

Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors

This paper describes the synthesis of a new class of peptidomimetic cysteine protease inhibitors based on a 1,4-benzodiazepine scaffold and on an electrophilic vinyl sulfone moiety. The former was introduced internally to a peptide sequence that mimics th