1013-01-0

Basic information

• Product Name: 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione
• Synonyms: 1,3-Dimethyl-1,2,3,4-tetrahydroquinazoline-2,4-dione;1,3-Dimethylquinazoline-2,4(1H,3H)-dione
• CAS NO: 1013-01-0
• Molecular Formula: C₁₀H₁₀N₂O₂
• Molecular Weight: 190.2
• Mol File: 1013-01-0.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 316.4°C at 760 mmHg
• Flash Point: 142.7°C
• Appearance: /
• Density: 1.256g/cm³
• Vapor Pressure: 0.000411mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione(1013-01-0)
• EPA Substance Registry System: 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione(1013-01-0)

Safety Data

• Hazardous Substances Data: 1013-01-0(Hazardous Substances Data)

Usage

General Description

1,3-dimethyl-2,4-(1H,3H)-quinazolinedione, also known as dimethylquinazolinedione, is a chemical compound with the molecular formula C10H10N2O2. It is a member of the quinazoline family and is commonly used as a building block in organic synthesis. 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione has important applications in the pharmaceutical industry, where it is used in the production of various drugs and pharmaceutical intermediates. 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione is also used in the synthesis of dyes, pigments, and other specialty chemicals. Its versatile reactivity and wide range of applications make it a valuable and important compound in the field of organic chemistry.

InChI:InChI=1/C10H10N2O2/c1-11-8-6-4-3-5-7(8)9(13)12(2)10(11)14/h3-6H,1-2H3

Upstream product

• 2525-16-8 O-methylcaprolactim 
• 86-96-4 1,2,3,4-tetrahydro-quinazoline-2,4-dione 
• 77-78-1 dimethyl sulfate 
• 6294-85-5 Perhydrochinazolin-2,4-dion 
• 74-83-9 methyl bromide 
• 33842-02-3 dichloromethylenedimethyliminium chloride 
• 85-91-6 Methyl N-methylanthranilate 
• 1359843-18-7 2-(1,3-dimethyl-4-oxo-1,2,3,4-tetrahydroquinazolin-2-ylidene)-1,3-dimethyl-1,2,3,4-tetrahydroquinazolin-4-one 
• 32212-33-2 N-methyl-2-(methylamino)benzamide 
• 604-50-2 glycosmicine 
• 74-88-4 methyl iodide 
• 2453-94-3 1,3-dimethyl-4-oxo-3,4-dihydroquinazolin-1-ium iodide 
• 201230-82-2 carbon monoxide 
• 119-68-6 N-Methylanthranilic acid 

Downstream Products

• 773877-44-4 1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonyl chloride 
• 1296732-14-3 C₁₇H₁₃BrN₂O₃ 
• 1296732-16-5 C₁₇H₁₃N₃O₅ 
• 1296732-12-1 C₁₈H₁₆N₂O₄ 
• 1296732-10-9 C₁₈H₁₆N₂O₃ 
• 1296732-08-5 C₁₇H₁₄N₂O₃ 

Relevant articles and documents

Harnessing selective PET and EnT catalysis by chlorophyll to synthesizeN-alkylated quinoline-2(1H)-ones, isoquinoline-1(2H)-ones and 1,2,4-trioxanes

Photocatalytic syntheses of quinoline-2(1H)-ones, isoquinoline-1(2H)-ones and 1,2,4-trioxanes were achieved by selective photo-induced electron transfer (PET) and energy transfer (EnT), respectively, by chlorophyll under visible light irradiation. Quinoli

Method for synthesizing quinazoline-2, 4 (1H, 3H)-diketone compound

The invention discloses a method for synthesizing a quinazoline-2, 4 (1H, 3H)-diketone compound, and belongs to the technical field of synthesis of nitrogen-containing heterocyclic compounds. According to the technical scheme, the method is characterized in that an anthranilic acid compound and an amine compound serve as reaction raw materials, CO serves as a carbonylation reagent, Pd (II) servesas a catalyst, KI or KI/AcOH serves as an additive, Cu (OAc) 2 or O2 or Cu (OAc) 2/O2 serves as an oxidizing agent, and the target product quinazoline-2, 4 (1H, 3H)-diketone compound is prepared through a one-pot multi-component reaction. The method has the advantages of simple and easily available raw material, short synthesis route, high atom economy and step economy, mild reaction conditions, diversified product structures, high yield of most target products and the like.

Synthesis and characterization of the first inhibitor of: N -acylphosphatidylethanolamine phospholipase D (NAPE-PLD)

N-Acylphosphatidylethanolamine phospholipase D (NAPE-PLD) is a membrane-associated zinc enzyme that catalyzes the hydrolysis of N-acylphosphatidylethanolamines (NAPEs) into fatty acid ethanolamides (FAEs). Here, we describe the identification of the first small-molecule NAPE-PLD inhibitor, the quinazoline sulfonamide derivative 2,4-dioxo-N-[4-(4-pyridyl)phenyl]-1H-quinazoline-6-sulfonamide, ARN19874.