1013-25-8

Basic information

• Product Name: 1-(2,5-DIMETHYLPHENYL)PIPERAZINE
• Synonyms: TIMTEC-BB SBB003654;1-(2,5-DIMETHYLPHENYL)PIPERAZINE;AKOS BBS-00003598;AKOS BB-5740;LABOTEST-BB LT00455255;1-(2,5-xylyl)piperazine;1-(2,5-DIMETHYLPHENYL)PIPERAZINE 99%;1-(2,5-Dimethylphenyl)piperazine,99%
• CAS NO: 1013-25-8
• Molecular Formula: C12H18N2
• Molecular Weight: 190.28
• EINECS: 213-795-6
• Mol File: 1013-25-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 42-46 °C
• Boiling Point: 154°C 10mm
• Flash Point: 154°C/10mm
• Appearance: white crystalline solid
• Density: 1.0320 (rough estimate)
• Vapor Pressure: 0.000146mmHg at 25°C
• Refractive Index: 1.5586 (estimate)
• Storage Temp.: 0-6°C
• Solubility: soluble in Methanol
• PKA: 9.05±0.10(Predicted)
• BRN: 611229
• CAS DataBase Reference: 1-(2,5-DIMETHYLPHENYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-DIMETHYLPHENYL)PIPERAZINE(1013-25-8)
• EPA Substance Registry System: 1-(2,5-DIMETHYLPHENYL)PIPERAZINE(1013-25-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 24/25-26
• RIDADR: 3259
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 1013-25-8(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline solid

InChI:InChI=1/C12H18N2/c1-10-3-4-11(2)12(9-10)14-7-5-13-6-8-14/h3-4,9,13H,5-8H2,1-2H3/p+1

Upstream product

• 95-78-3 2,5-Dimethylaniline 

Downstream Products

• 78069-86-0 1-(2,5-Dimethyl-phenyl)-4-(3-nitro-pyridin-4-yl)-piperazine 
• 198286-38-3 N-[3-{4-(2,5-dimethylphenyl)-1piperazinyl}-propyl]-N-methyl-α-phenyl-benzeneacetamide 
• 1061701-76-5 ethyl 4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butanoate 
• 1181802-58-3 4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butanenitrile 
• 1181802-65-2 3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propanenitrile 
• 1072849-74-1 (1R,2R)-{2-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-1,2-dihydro-naphthalen-1-yl}-carbamic acid tert-butyl ester 
• 1321841-09-1 C₃₆H₄₅N₇O₅S 
• 120004-74-2 7-{3-[4-(2,5-Dimethyl-phenyl)-piperazin-1-yl]-propoxy}-3,4-dihydro-1H-quinolin-2-one 
• 57961-95-2 2-{2-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-ethyl}-quinoline 
• 90126-01-5 1-(2,5-Dimethyl-phenyl)-4-(2-pyridin-2-yl-ethyl)-piperazine; compound with (E)-but-2-enedioic acid 

Relevant articles and documents

Anti-tumor compound of targeting Neddylation path

The invention discloses an anti-tumor compound of a targeting Neddylation path. The compound can be represented by a structural formula shown as a general formula I, a general formula II, a general formula III, a general formula IV, a general formula V, a general formula VI or a general formula VII. The compound provided by the invention has good anti-tumor activity; a plurality of compounds are close to a positive control drug MLN4924 and can be used as the good anti-tumor compound. The compound and a composition, provided by the invention, can be used with other drugs to provide combined therapy, and the other drugs can form a part of the same composition or can be used as different components for drug administration at the same time or at different time.

Glucagon antagonists/inverse agonists

Non-peptide compounds comprising a central hydrazide motif and methods for the synthesis thereof are disclosed. The compounds act to antagonize the action of the glucagon peptide hormone.