1013-27-0

Basic information

• Product Name: 1-(2,5-DICHLOROPHENYL)PIPERAZINE
• Synonyms: 1-(2,5-DICHLOROPHENYL)PIPERAZINE;1-(2,5-DICHLOROPHENYL)PIPERAZINE HYDROCHLORIDE;N-(2,5-Dichlorophenyl)-piperazine
• CAS NO: 1013-27-0
• Molecular Formula: C₁₀H₁₂Cl₂N₂
• Molecular Weight: 231.12
• Product Categories: Piperidines, Piperidones, Piperazines
• Mol File: 1013-27-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 125-128 °C(Press: 0.5 Torr)
• Appearance: /
• Density: 1.272±0.06 g/cm3(Predicted)
• PKA: 8.71±0.10(Predicted)
• CAS DataBase Reference: 1-(2,5-DICHLOROPHENYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-DICHLOROPHENYL)PIPERAZINE(1013-27-0)
• EPA Substance Registry System: 1-(2,5-DICHLOROPHENYL)PIPERAZINE(1013-27-0)

Safety Data

• Hazardous Substances Data: 1013-27-0(Hazardous Substances Data)

Usage

Description

1-(2,5-Dichlorophenyl)piperazine, commonly known as DCPP, is a piperazine derivative with a molecular structure that features a piperazine ring connected to a phenyl ring, with two chlorine atoms positioned at the 2 and 5 positions. This chemical compound is widely recognized for its use as an ingredient in various industrial and consumer products.

Uses

Used in Pharmaceutical Industry:
1-(2,5-Dichlorophenyl)piperazine is used as an intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs and medications. Its unique molecular structure allows for the creation of a variety of compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(2,5-Dichlorophenyl)piperazine is employed as an intermediate, playing a crucial role in the production of agrochemicals. This includes the synthesis of pesticides and other compounds designed to protect crops and enhance agricultural productivity.
Used in Dye and Pigment Production:
1-(2,5-Dichlorophenyl)piperazine is used as a precursor in the manufacturing of dyes and pigments, which are essential for coloring textiles, plastics, and other materials. Its chemical properties enable the creation of a range of vibrant and stable colorants.
Used in Insecticide Production:
As a precursor, 1-(2,5-Dichlorophenyl)piperazine is also utilized in the production of insecticides, helping to control pests and protect crops from damage. Its role in the synthesis of these compounds is vital for the development of effective pest management strategies.
Used in Environmental Research:
1-(2,5-Dichlorophenyl)piperazine has been identified as a potential environmental pollutant, found in water sources and wildlife. It is used as a subject of study in ongoing research to understand the potential risks and impacts of DCPP on human health and the environment, helping to inform regulatory measures and pollution control efforts.

Upstream product

• 95-82-9 2,5 dichloroaniline 
• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 

Downstream Products

• 914772-92-2 7-{2-[4-(2,5-dichlorophenyl)piperazin-1-yl]ethoxy}-4-methyl-2H-chromen-2-one 
• 682346-20-9 C₂₀H₁₆Cl₂N₂O₃ 
• 321602-03-3 2-[4-(2,5-dichlorophenyl)-1-piperazinyl]-acetonitrile 
• 688011-09-8 4-[4-(2,5-dichlorophenyl)-1-piperazinyl]butylamine 
• 55485-12-6 3-[4-(2,5-dichlorophenyl)piperazino]-1-propanamine 
• 688011-15-6 N-[4-[4-(2,5-dichlorophenyl)-1-piperazinyl]butyl]phthalimide 
• 688011-12-3 N-{3-[4-(2,5-dichloro-phenyl)-piperazin-1-yl]-propyl}-phthalimide 
• 120004-70-8 7-{3-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-propoxy}-3,4-dihydro-1H-quinolin-2-one 
• 120004-62-8 5-{3-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-propoxy}-3,4-dihydro-1H-quinolin-2-one 
• 103247-56-9 2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-N-(7-hydroxy-2,2,4,6-tetramethyl-indan-1-yl)-acetamide 

Relevant articles and documents

Practical method for parallel synthesis of diversely substituted 1-phenylpiperazines

A simple and practical method to prepare 'libraries' of substituted 1-phenylpiperazine building blocks in parallel format has been developed.