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cis-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1013099-80-3 Structure
  • Basic information

    1. Product Name: cis-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol
    2. Synonyms:
    3. CAS NO:1013099-80-3
    4. Molecular Formula:
    5. Molecular Weight: 379.3
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1013099-80-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: cis-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: cis-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol(1013099-80-3)
    11. EPA Substance Registry System: cis-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol(1013099-80-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1013099-80-3(Hazardous Substances Data)

1013099-80-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1013099-80-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,3,0,9 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1013099-80:
(9*1)+(8*0)+(7*1)+(6*3)+(5*0)+(4*9)+(3*9)+(2*8)+(1*0)=113
113 % 10 = 3
So 1013099-80-3 is a valid CAS Registry Number.

1013099-80-3Relevant articles and documents

Structure-based design, SAR analysis and antitumor activity of PI3K/mTOR dual inhibitors from 4-methylpyridopyrimidinone series

Cheng, Hengmiao,Hoffman, Jacqui E.,Le, Phuong T.,Pairish, Mason,Kania, Robert,Farrell, William,Bagrodia, Shubha,Yuan, Jing,Sun, Shaoxian,Zhang, Eric,Xiang, Cathy,Dalvie, Deepak,Rahavendran, Sadayappan V.

supporting information, p. 2787 - 2792 (2013/07/04)

PI3K, AKT and mTOR, key kinases from a frequently dysregulated PI3K signaling pathway, have been extensively pursued to treat a variety of cancers in oncology. Clinical trials of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR, from 4-methylpyridopyrimidinone series, led to the discovery of a metabolite with a terminal carboxylic acid, PF-06465603. This paper discusses structure-based drug design, SAR and antitumor activity of the MPP derivatives with a terminal alcohol, a carboxylic acid or a carboxyl amide.

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