10133-20-7Relevant articles and documents
Synthesis of Thia-Analogues of Calothrixin B Involving FeCl3-Mediated Domino Reaction
Ramalingam, Bose Muthu,Moorthy, Nachiappan Dhatchana,Vellaichamy, Elangovan,Mohanakrishnan, Arasambattu K.
, p. 133 - 137 (2017)
The total synthesis of thiacalothrixins, an isostere of the biologically important carbazoloquinone alkaloid calothrixin B, was achieved from ethyl benzo[b]thiophene-2-carboxylate. Alternatively, the multi-step synthesis of thiaisocalothrixins could be achieved from 3-methylbenzo[b]thiophene. A preliminary in vitro cytotoxicity evaluation of the synthesized thia analogues of calothrixins displayed promising potential against cancer cell cultures.
NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS
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Page/Page column 139, (2011/06/19)
The invention relates to novel heterocyclic acrylamide compounds (I), to the preparation of the compounds and intermediates used therein, to the use of the compounds as antibacterial medicaments and pharmaceutical compositions containing the compounds.
Tandem free-radical addition/substitution chemistry and its application to the preparation of novel AT1 receptor antagonists
Staples, Maree K.,Grange, Rebecca L.,Angus, James A.,Ziogas, James,Tan, Nichole P. H.,Taylor, Michelle K.,Schiesser, Carl H.
experimental part, p. 473 - 479 (2011/03/17)
Benzothiophene and benzoselenophene analogues of the thiophene-containing antihypertensives milfasartan and eprosartan were prepared and tested for AT1 receptor antagonist properties. While the sulfur-containing systems were prepared following
