10133-36-5Relevant articles and documents
SELECTIVE HDAC1 AND HDAC2 INHIBITORS
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, (2014/05/20)
Provided herein are compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with HDAC activity, particularly diseases or disorders that involve activity of HDAC1 and/or HDAC2. Such diseases include cancer, sickle-cell anemia, beta-thalassemia, and HIV.
Synthesis of Substituted Benzothienopyrazines
Cannizzo, Sergio,Guerrera, Francesco,Siracusa, Maria Angela,Corsaro, Antonino
, p. 2175 - 2179 (2007/10/02)
The synthesis of a series of novel 1-unsubstituted and 1-alkyl-1,2,3,4-tetrahydrobenzothienopyrazine-2,3-diones 4a-d and their corresponding dialkylaminoalkylamino derivatives 6a-d starting from 2-nitro-3-bromobenzothiophene is described.The
Bromonitromethane, a Versatile Electrophile: Reactions with Thiolates
Fishwick, Brian R.,Rowles, David K.,Stirling, Charles J. M.
, p. 834 - 835 (2007/10/02)
Thiolate ions react with bromonitromethane to give nitronate ion and, initially, sulphenyl bromide which reacts with further thiolate ion to give disulphide; when the disulphide bears an appropriately placed nitrile function, intramolecular attack by the nitronate ion at this function and subsequent intramolecular displacement of thiolate ion yields aminothiophenes.