10134-91-5

Usage

Uses

Used in Pharmaceutical Industry:
BENZO[B]THIOPHENE-7-CARBALDEHYDE is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of new medicines with potential therapeutic applications.
Used in Agricultural Industry:
In the agricultural sector, BENZO[B]THIOPHENE-7-CARBALDEHYDE is utilized as a precursor in the production of agrochemicals. Its involvement in the synthesis of these compounds contributes to the development of effective pest control agents and other agricultural products.
Used in Dye Manufacturing:
BENZO[B]THIOPHENE-7-CARBALDEHYDE is employed as a chemical intermediate in the manufacturing of dyes. Its properties enable the creation of a diverse range of colorants used in various industries, including textiles and plastics.
Used in Fragrance Industry:
BENZO[B]THIOPHENE-7-CARBALDEHYDE is also used as a building block in the production of fragrances. Its incorporation into fragrance formulations contributes to the creation of unique scents for various applications, such as perfumes and cosmetics.
Used in Flavoring Agent Production:
BENZO[B]THIOPHENE-7-CARBALDEHYDE plays a role in the synthesis of flavoring agents, adding to the complexity and variety of tastes in the food and beverage industry.
Safety Precautions:
Due to the reactivity and potential hazards of BENZO[B]THIOPHENE-7-CARBALDEHYDE, it is crucial to follow proper handling and safety procedures when working with this chemical compound. This ensures the safety of individuals and the environment during its use in various applications.

InChI:InChI=1/C9H6OS/c10-6-8-3-1-2-7-4-5-11-9(7)8/h1-6H

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 51830-53-6 7-Hydroxymethylbenzo[b]thiophene 
• 1423-61-6 7-bromobenzo(b)thiophene 

Downstream Products

• 1037763-23-7 C₂₅H₁₈F₂N₂O₃S 
• 1037763-25-9 C₂₄H₁₆F₂N₂O₃S 
• 1037763-27-1 C₂₅H₁₉F₂N₃O₄S₂ 
• 1037758-60-3 C₂₄H₁₇F₂N₃O₄S₂ 
• 1037758-22-7 6-(2,5-difluorobenzyl)-8-(2-oxo-1,2-dihydropyridin-3-yl)-6H-thieno[2,3-e]indole-7-carboxylic acid 

Relevant academic research and scientific papers

BICYCLIC COMPOUNDS

Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.

Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase

The characterization of HCV genome has identified various vital functional proteins involved in the life cycle of hepatitis C virus. This has resulted in many novel enzymatic targets that are potential for development of therapeutic agents. The HCV RNA de

BENZISOXAZOLE COMPOUND

Disclosed is a compound represented by the general formula (I) or a salt thereof: wherein any one of R1, R2 and R3 represents a group represented by the formula: -(CH2)m-NR11R12 (wherein m is 1 or 2; and R11 and R12 independently represent a hydrogen atom or a C1-6 alkyl group or may, together with a nitrogen atom to which R11 and R12 are bound, form a 4- or 5-membered cyclic group); the remaining two or R1, R2 and R3 independently represent a group represented by the formula: -(O)n-R21 (wherein n is 0 or 1; and R21 represents a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, or the like); and R4 represents a C1-6 alkyl group which may have a substituent or the like.

4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS

The present invention relates to 4,5-ring annulated indole derivatives, compositions comprising at least one 4,5-ring annulated indole derivatives, and methods of using the 4,5-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient. Wherein ring Z, of formula (I), is a cyclopentyl, cyclopentenyl, 5-membered heterocycloalkyl, 5-membered heterocycloalkenyl or 5-membered heteroaryl ring.

PURINE DERIVATIVES AS KINASE INHIBITORS

The present invention provides kinase inhibitors of Formula I.

Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds

Compounds of the formula: STR1 wherein R1 is (1) hydrogen, (2) C1 to C4 alkyl, (3) C2 to C4 alkenyl, or (4) NR2 R3, wherein R2 and R3 are independently selected from (1) hydrogen, (2) C1 to C4 alkyl and (3) hydroxyl, but R2 and R3 are not simultaneously hydroxyl; wherein X is oxygen, sulfur, SO2, or NR4, wherein R4 is (1) hydrogen, (2) C1 to C6 alkyl, (3) C1 to C6 alkoyl, (4) aroyl, or (5) alkylsulfonyl; A is selected from C1 to C6 alkylene and C2 to C6 alkenylene; n is 1-5; Y is selected independently at each occurrence from (1) hydrogen, (2) halogen, (3) hydroxy, (4) cyano, (5) halosubstituted alkyl, (6) C1 to C12 alkyl, (7) C2 to C12 alkenyl, (8) C1 to C12 alkoxy, (9) C3 to C8 cycloalkyl, (10) C1 -C8 thioalkyl, (11) aryl, (12) aryloxy, (13) aroyl, (14) C1 to C12 arylalkyl, (15) C2 to C12 arylalkenyl, (16) C1 to C12 arylalkoxy, (17) C1 to C12 arylthioalkoxy, and substituted derivatives of (18) aryl, (19) aryloxy, (20) aroyl, (21) C1 to C12 arylalkyl, (22) C2 to C12 arylalkenyl, (23) C1 to C12 arylalkoxy, or (24) C1 to C12 arylthioalkoxy, wherein substituents are selected from halo, nitro, cyano, C1 to C12 alkyl, alkoxy, and halosubstituted alkyl; Z is oxygen or sulfur; and M is hydrogen, a pharmaceutically acceptable cation, aroyl, or C1 to C12 alkoyl, are potent inhibitors of 5- and/or 12-lipoxygenase enzymes. Also disclosed are lipoxygenase inhibiting compositions and a method for inhibiting lipoxygenase activity.