1013401-21-2Relevant articles and documents
Design and synthesis of BACE1 inhibitors containing a novel norstatine derivative (2R,3R)-3-amino-2-hydroxy-4-(phenylthio)butyric acid
Ziora, Zyta,Kasai, Soko,Hidaka, Koushi,Nagamine, Ayaka,Kimura, Tooru,Hayashi, Yoshio,Kiso, Yoshiaki
, p. 1629 - 1633 (2007/10/03)
A novel norstatine derivative, phenylthionorstatine [(2R,3R)-3-amino-2-hydroxy-4-(phenylthio)butyric acid; Ptns], containing a hydroxymethylcarbonyl (HMC) isostere was designed, synthesized, and stereochemically determined. Then, Ptns was introduced into