1013402-33-9

Upstream product

• 10397-13-4 4,6-dichloro-2-(morpholine-4-yl)pyrimidine 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 1013402-34-0 N-[2-[(6-chloro-2-morpholin-4-yl-pyrimidin-4-yl)amino]phenyl]-2,2,2-trifluoro-acetamide 

Relevant academic research and scientific papers

PYRIMIDINE DERIVATIVES

The invention concerns pyrimidine derivatives of Formula (I), wherein each of p, R1, R2, q, R3, r, R4, X1 and Q1 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in a method for producing an anti-proliferative effect in a warm blooded animal such as man.

4-BENZIMIDAZOLYL-2-MORPHOLINO-6-PIPERAZINYLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

The invention concerns pyrimidine derivatives of Formula (I): wherein each of p, R1, R2, q, R3, r, R4, X1 and Q1 have any of the meanings defined in the description; processes for their pre

6-BENZIMIDAZ0LYL-2-M0RPH0LIN0-4- (AZETIDINE, PYRROLIDINE, PIPERIDINE OR AZEPINE) PYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

The invention concerns pyrimidine derivatives of Formula (I): wherein each of p, R1, R2, q, R3, r, R4, s, t, X1 and Q1 have any of the meanings defined in the description; processes for the