1013421-33-4Relevant articles and documents
Inhibition of tubulin polymerization by select alkenyldiarylmethanes
Cullen, Matthew D.,Sarkar, Taradas,Hamel, Ernest,Hartman, Tracy L.,Watson, Karen M.,Buckheit Jr., Robert W.,Pannecouque, Christophe,De Clercq, Erik,Cushman, Mark
, p. 469 - 473 (2008)
During studies on the alkenyldiarylmethane (ADAM) class of non-nucleoside reverse transcriptase inhibitors (NNRTIs), analogues were discovered that exhibit low micromolar and submicromolar cytotoxicities. Since the ADAMs are structurally related to the tu