10135-17-8

Basic information

• Product Name: 3-phenethyloxazolidin-2-one
• Synonyms: 3-phenethyloxazolidin-2-one
• CAS NO: 10135-17-8
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 0
• Mol File: 10135-17-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 398.8°C at 760 mmHg
• Flash Point: 195°C
• Appearance: /
• Density: 1.154g/cm³
• Vapor Pressure: 1.44E-06mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: 3-phenethyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenethyloxazolidin-2-one(10135-17-8)
• EPA Substance Registry System: 3-phenethyloxazolidin-2-one(10135-17-8)

Safety Data

• Hazardous Substances Data: 10135-17-8(Hazardous Substances Data)

Usage

General Description

3-phenethyloxazolidin-2-one, also known as PEtO, is a chemical compound with the molecular formula C10H11NO2. It is a heterocyclic organic compound that contains an oxazolidine ring and a phenethyl group. This chemical has been studied for its role as an intermediate in the synthesis of various pharmaceuticals and natural products. PEtO has also been shown to have potential as a chiral building block in organic synthesis, making it a valuable compound in the field of medicinal and synthetic chemistry. Additionally, it has been investigated for its biological activity and potential therapeutic applications.

InChI:InChI=1/C11H13NO2/c13-11-12(8-9-14-11)7-6-10-4-2-1-3-5-10/h1-5H,6-9H2

Upstream product

• 497-25-6 dimethylenecyclourethane 
• 64-04-0 phenethylamine 
• 888329-88-2 3-(2-phenylethynyl)oxazolidin-2-one 
• 124-38-9 carbon dioxide 
• 107-06-2 1,2-dichloro-ethane 

Relevant articles and documents

Organocatalytic diimide reduction of enamides in water

Bridged flavinium organocatalysts have displayed efficacy in the diimide mediated reduction of enamides in aqueous conditions. This represents the first diimide reduction of an electron rich alkene and offers a clean alternative to the use of alkylating agents for N-alkylation.

Cooperative Catalysis of Ru(III)-Porphyrin in CO2-Involved Synthesis of Oxazolidinones

CO2-transformations into high value-added products have become a fascinating area in green chemistry. Herein, a Ru(III)-porphyrin catalyst (RuCl3 ? 3H2O?H2TPP) was found highly efficient in the three-component reaction of CO2, aliphatic amines and dichloroethane (or its derivative) for synthesis of oxazolidinones in the yields of 71～91%. It was indicated by means of the control experiments and UV-vis spectra that CO2 was stoichiometrically activated by the involved aliphatic amine substrates to form a stable carbamate salt while 1,2-dichloroethane (or its derivative) was independently activated by the involved Ru(III)-porphyrin catalyst. The combination of CO2-activation by aliphatic amines with 1,2-dichloroethane activation by Ru(III)-porphyrin catalyst cooperatively contributed to this successful transformation.