1013648-04-8

Basic information

• Product Name: methyl 2,6-dichloro-4-methylnicotinate
• Synonyms: methyl 2,6-dichloro-4-methylnicotinate;2,6-Dichloro-4-methylnicotinic acid methyl ester;2,6-Dichloro-4-methylpyridine-3-carboxylic acid methyl ester
• CAS NO: 1013648-04-8
• Molecular Formula: C₈H₇Cl₂NO₂
• Molecular Weight: 220.05268
• Mol File: 1013648-04-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 292℃
• Flash Point: 130℃
• Appearance: /
• Density: 1.369
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -3.75±0.10(Predicted)
• CAS DataBase Reference: methyl 2,6-dichloro-4-methylnicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,6-dichloro-4-methylnicotinate(1013648-04-8)
• EPA Substance Registry System: methyl 2,6-dichloro-4-methylnicotinate(1013648-04-8)

Safety Data

• Hazardous Substances Data: 1013648-04-8(Hazardous Substances Data)

Usage

General Description

Methyl 2,6-dichloro-4-methylnicotinate is a chemical compound that belongs to the class of organic compounds known as pyridine carboxylic acids and derivatives. It is a derivative of nicotinic acid, which is a precursor to NAD+ and NADH coenzymes involved in numerous biochemical reactions. Methyl 2,6-dichloro-4-methylnicotinate is used in the synthesis of various pharmaceuticals and agrochemicals due to its potential biological activities. It exhibits antiproliferative and anti-inflammatory properties, making it an important compound in drug development. Additionally, it is used in the production of insecticides and herbicides, making it essential in agricultural applications.

Upstream product

• 56950-89-1 2,6-dichloro-4-methylnicotinoyl chloride 
• 62774-90-7 2,6-dichloro-4-methyl-nicotinic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 1013648-05-9 methyl 2-chloro-6-(2-fluoro-3-methoxyphenyl)-4-methylnicotinate 
• 1421253-88-4 methyl 2-chloro-4-methyl-6-(3-methyl-1-tosyl-1H-indol-4-yl)nicotinate 

Relevant articles and documents

PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS

The present disclosure provides selective phosphoinositide 3-kinase gamma inhibitors of Formula (I) including (I-a), (I-b), (I-c), and (I-d), or pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of conditions mediated

SUBSTITUTED 6-AMINO-NICOTINAMIDES AS KCNQ2/3 MODULATORS

Substituted 6-amino-nicotinamides, pharmaceutical compositions containing these compounds and also use of these compounds in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF

The present invention relates to novel 2-phenoxy-6-phenyl- and 2-phenoxy-6-pyridylnicotinic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prophylaxis of cardiovascular disorders, especially of dyslipidemias, arteriosclerosis and heart failure.