1013656-78-4

Basic information

• Product Name: tert-butyl [(1R)-3-[(5R,8R)-dimethyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate
• CAS NO: 1013656-78-4
• Molecular Weight: 535.489
• Mol File: 1013656-78-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl [(1R)-3-[(5R,8R)-dimethyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [(1R)-3-[(5R,8R)-dimethyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate(1013656-78-4)
• EPA Substance Registry System: tert-butyl [(1R)-3-[(5R,8R)-dimethyl-3-(trifluoromethyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-yl]-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate(1013656-78-4)

Safety Data

• Hazardous Substances Data: 1013656-78-4(Hazardous Substances Data)

Upstream product

• 780754-27-0 5,8-dimethyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine 
• 486460-00-8 (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 

Relevant articles and documents

Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from β-aminoamides bearing subsituted triazolopiperazines

A series of β-aminoamides bearing triazolopiperazines have been discovered as potent, selective, and orally active dipeptidyl peptidase IV (DPP-4) inhibitors by extensive structure-activity relationship (SAR) studies around the triazolopiperazine moiety.